ACE inhibitor-induced angioedema of the small intestine: a case report

Angiotensin-converting enzyme (ACE) inhibitors are standard medication in treating hypertension, heart failure and diabetic nephropathy. The most common side effects are cough and angioneurotic oedema of the upper airways. A less familiar side effect is the ACE inhibition-induced visceral angioedema...

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Bibliographic Details
Published in:Acta Cardiologica 2011-10, Vol.66 (5), p.645-648
Main Authors: Cuypers, Sofie, Van Meerbeeck, Stephen, De Pauw, Michel
Format: Article
Language:English
Subjects:
Adult
Angioedema - chemically induced
Angiotensin-Converting Enzyme Inhibitors - administration & dosage
Angiotensin-Converting Enzyme Inhibitors - adverse effects
Female
Heart Failure - drug therapy
Humans
Intestinal Diseases - chemically induced
Intestinal Diseases - diagnosis
Intestine, Small - drug effects
Intestine, Small - pathology
Lisinopril - administration & dosage
Lisinopril - adverse effects
Time Factors
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Summary:Angiotensin-converting enzyme (ACE) inhibitors are standard medication in treating hypertension, heart failure and diabetic nephropathy. The most common side effects are cough and angioneurotic oedema of the upper airways. A less familiar side effect is the ACE inhibition-induced visceral angioedema. We report the case of a young female patient with recent diagnosis of heart failure (dilated cardiomyopathy due to viral myocarditis), who developed angioedema of the small intestine three weeks after initiating treatment with lisinopril. Symptoms resolved within days once administration of the drug was stopped.
ISSN:0001-5385
1784-973X
0373-7934
DOI:10.1080/AC.66.5.2131092