Relationship between risk stratification at admission and treatment effects of early invasive management following fibrinolysis: insights from the Trial of Routine ANgioplasty and Stenting After Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI)

Aims We sought to determine the effectiveness of early routine percutaneous coronary intervention (PCI) post-fibrinolysis for ST-elevation myocardial infarction (STEMI) in relation to baseline risk status. Methods and results In this post hoc subgroup analysis of Trial of Routine Angioplasty and Ste...

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Bibliographic Details
Published in:European heart journal 2011-08, Vol.32 (16), p.1994-2002
Main Authors: Yan, Andrew T., Yan, Raymond T., Cantor, Warren J., Borgundvaag, Bjug, Cohen, Eric A., Fitchett, David H., Dzavik, Vladimir, Ducas, John, Tan, Mary, Casanova, Amparo, Goodman, Shaun G.
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary
Biological and medical sciences
Cardiology. Vascular system
Coronary heart disease
Diseases of the cardiovascular system
Female
Fibrinolytic Agents - therapeutic use
Heart
Humans
Male
Medical sciences
Middle Aged
Myocardial Infarction - therapy
Myocardial Reperfusion - methods
Myocarditis. Cardiomyopathies
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Recurrence
Risk Assessment
Stents
Tissue Plasminogen Activator - therapeutic use
Treatment Outcome
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Summary:Aims We sought to determine the effectiveness of early routine percutaneous coronary intervention (PCI) post-fibrinolysis for ST-elevation myocardial infarction (STEMI) in relation to baseline risk status. Methods and results In this post hoc subgroup analysis of Trial of Routine Angioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER-AMI), we stratified 1059 STEMI patients receiving tenecteplase into low-intermediate [Global Registry of Acute Coronary Events (GRACE) risk score
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehr008