Subcutaneous myxopapillary ependymal rest: A potential sign of spinal dysraphism

Subcutaneous myxopapillary ependymal rests are heterotopias of neuroglial tissue that present in the subcutaneous tissue of the sacrococcygeal region. We report a case which presented as a flesh-colored, pedunculated papule near the gluteal cleft. The presence of a congenital lesion near the midline...

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Bibliographic Details
Published in:Journal of the American Academy of Dermatology 2011-10, Vol.65 (4), p.851-854
Main Authors: Burdick, Laura M., MD, Bergfeld, Wilma, MD, Somani, Najwa, MD, Piliang, Melissa, MD
Format: Article
Language:English
Subjects:
Biological and medical sciences
Choristoma - pathology
Dermatology
Diseases of the osteoarticular system
Diseases of the spine
Ependyma - pathology
Ependymoma - diagnosis
Ependymoma - pathology
Female
Humans
Infant
Medical sciences
Sacrococcygeal Region - pathology
Spinal Dysraphism - pathology
Subcutaneous Tissue - pathology
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Description
Summary:Subcutaneous myxopapillary ependymal rests are heterotopias of neuroglial tissue that present in the subcutaneous tissue of the sacrococcygeal region. We report a case which presented as a flesh-colored, pedunculated papule near the gluteal cleft. The presence of a congenital lesion near the midline of the spine should alert the clinician to the possibility of spinal dysraphism and necessitates imaging before biopsy. Subcutaneous myxopapillary rests are benign but must be distinguished from their histologic mimic, subcutaneous myxopapillary ependymomas, which are low-grade tumors with metastatic potential.
ISSN:0190-9622
1097-6787
DOI:10.1016/j.jaad.2009.11.027