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A Remarkably Simple Protocol for the N-Formylation of Amino Acid Esters and Primary Amines

A simple, convenient, and wide scope protocol for the N-formylation of amino acid esters and primary amines has been developed utilizing only imidazole in warm DMF.

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Bibliographic Details
Published in:Organic letters 2011-08, Vol.13 (15), p.3952-3955
Main Authors: Suchý, Mojmír, Elmehriki, Adam A. H, Hudson, Robert H. E
Format: Article
Language:English
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Summary:A simple, convenient, and wide scope protocol for the N-formylation of amino acid esters and primary amines has been developed utilizing only imidazole in warm DMF.
ISSN:1523-7060
1523-7052
DOI:10.1021/ol201475j