Clinician-trialist rounds: 5. Cointervention bias – how to diagnose it in their trial and prevent it in yours

A primer on preventing or overcoming cointervention bias in clinical trials is presented. Among other steps, one should think like a trialist: search for any unequal application of these clinically-relevant cointerventions to the experimental and control groups, and if present consider the impact of...

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Bibliographic Details
Published in:Clinical trials (London, England) England), 2011-08, Vol.8 (4), p.440-442
Main Author: Sackett, David L
Format: Article
Language:English
Subjects:
Bias
Clinical trials
Controlled Clinical Trials as Topic - methods
Controlled Clinical Trials as Topic - statistics & numerical data
Data Interpretation, Statistical
Design
Humans
Risk
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Summary:A primer on preventing or overcoming cointervention bias in clinical trials is presented. Among other steps, one should think like a trialist: search for any unequal application of these clinically-relevant cointerventions to the experimental and control groups, and if present consider the impact of the resulting cointervention bias on the trial results.
ISSN:1740-7745
1740-7753
DOI:10.1177/1740774511410995