Morphine-conditioned cue alters c-Fos protein expression in the brain of crayfish

Highlights ► A repeated or single injection of morphine serves as reward when paired with a distinct visual cue. ► The brains of crayfish were more active during exposure to the cue-elicited drug seeking. ► Morphine-conditioned cue alters c-Fos expression in the brain of crayfish.

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Bibliographic Details
Published in:Brain research bulletin 2011-07, Vol.85 (6), p.385-395
Main Authors: Dziopa, Leah, Imeh-Nathaniel, Adebobola, Baier, Dana, Kiel, Michael, Sameera, Sayeed, Brager, Adam, Beatriz, Vega, Nathaniel, Thomas I
Format: Article
Language:English
Subjects:
Animals
Astacoidea - anatomy & histology
Astacoidea - physiology
Behavior, Animal - drug effects
Behavioral sensitization
Brain - drug effects
Brain - metabolism
c-Fos
Cambaridae
Conditioning (Psychology) - drug effects
CPP
Crayfish
Cues
Drug addiction
Freshwater
Locomotion
Male
Morphine
Morphine - pharmacology
Motor Activity - drug effects
Narcotics - pharmacology
Neurology
Orconectes rusticus
Proto-Oncogene Proteins c-fos - metabolism
Random Allocation
Reward
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Description
Summary:Highlights ► A repeated or single injection of morphine serves as reward when paired with a distinct visual cue. ► The brains of crayfish were more active during exposure to the cue-elicited drug seeking. ► Morphine-conditioned cue alters c-Fos expression in the brain of crayfish.
ISSN:0361-9230
1873-2747
DOI:10.1016/j.brainresbull.2011.04.003