Impact of liver steatosis on the correlation between liver stiffness and fibrosis measured by transient elastography in patients coinfected with human immunodeficiency virus and hepatitis C virus

We assessed the effect of different hepatic conditions such as fibrosis, steatosis and necroinflammatory activity on liver stiffness as measured by transient elastography in HIV/HCV‐coinfected patients. We studied all consecutive HIV/HCV‐coinfected patients who underwent liver biopsy and elastograph...

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Bibliographic Details
Published in:Journal of viral hepatitis 2011-07, Vol.18 (7), p.e278-e283
Main Authors: Sánchez-Conde, M., Montes Ramírez, M. L., Bellón Cano, J. M., Caminoa, A., Rodríguez, F. Álvarez, Garcia, J. González, Martín, P. Miralles, Bernardino de la Serna, I., Bernardo de Quirós, J. C. López, Arribas López, J. R., Ochaíta, J. Cosín, Pascual Pareja, J. F., Alvarez, E., Berenguer, J. B.
Format: Article
Language:English
Subjects:
Adult
Coinfection
Elasticity
Elasticity Imaging Techniques
Fatty Liver - complications
Fatty Liver - pathology
Female
Hepatitis C - complications
Hepatitis C virus
HIV
HIV Infections - complications
HIV-HCV coinfected
Human immunodeficiency virus
Humans
Liver
Liver Cirrhosis - complications
Liver Cirrhosis - pathology
liver fibrosis
liver steatosis
Male
Middle Aged
Regression analysis
transient elastography
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Summary:We assessed the effect of different hepatic conditions such as fibrosis, steatosis and necroinflammatory activity on liver stiffness as measured by transient elastography in HIV/HCV‐coinfected patients. We studied all consecutive HIV/HCV‐coinfected patients who underwent liver biopsy and elastography between January 2007 and December 2008. Liver fibrosis was staged following METAVIR Cooperative Study Group criteria. Steatosis was categorized according to the percentage of affected hepatocytes as low (≤10%), moderate (
ISSN:1352-0504
1365-2893
DOI:10.1111/j.1365-2893.2010.01407.x