Faster evolution of Z-linked duplicate genes in chicken

It has been shown that duplicate genes on the X chromosome evolve much faster than duplicate genes on autosomes in Drosophila melanogaster. However, whether this phenomenon is general and can be applied to other species is not known. Here we examined this issue in chicken that have heterogametic fem...

Full description

Saved in:
Bibliographic Details
Published in:Journal of genetics and genomics 2010-10, Vol.37 (10), p.695-702
Main Authors: Yan, Li, Liqing, Zhang, Dexiang, Zhang, Xiquan, Zhang, Xuemei, Lu
Format: Article
Language:chi ; eng
Subjects:
Animals
Cerebellum - metabolism
chicken genome
Chickens - genetics
Drosophila melanogaster
Evolution, Molecular
faster evolution
Female
gene duplication
gene expression
Gene Expression Profiling
Genes, Duplicate - genetics
Genetic Linkage
Liver - metabolism
Male
Oligonucleotide Array Sequence Analysis
Ovary - metabolism
Sex Chromosomes - genetics
Sex Factors
Testis - metabolism
Z chromosome
Z染色体
常染色体
挂钩
染色体复制
演化
进化速度
重复基因
鸡
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:It has been shown that duplicate genes on the X chromosome evolve much faster than duplicate genes on autosomes in Drosophila melanogaster. However, whether this phenomenon is general and can be applied to other species is not known. Here we examined this issue in chicken that have heterogametic females （females have ZW sex chromosome）. We compared sequence divergence of duplicate genes on the Z chromosome with those on autosomes. We found that duplications on the Z chromosome indeed evolved faster than those on autosomes and show distinct patterns of molecular evolution from autosomal duplications. Examination of the expression of duplicate genes revealed an enrichment of duplications on the Z chromosome having male-biased expression and an enrichment of duplications on the autosomes having female-biased expression. These results suggest an evolutionary trend of the recruitment of duplicate genes towards reproduction-specific function. The faster evolution of duplications on Z than on the autosomes is most likely contributed by the selective forces driving the fixation of adaptive mutations on Z. Therefore, the common phenomena observed in both flies and chicken suggest that duplicate genes on sex chromosomes have distinct dynamics and are more influenced by natural selection than autosomal duplications, regardless of the kind of sex determination systems.
ISSN:1673-8527
DOI:10.1016/S1673-8527(09)60087-4