Oncologic and functional results after transhyoid surgical approach for cancer of the base of tongue

Background The optimal treatment for base of tongue cancer remains unclear, especially in advanced stages. Methods We retrospectively review 84 previously untreated patients that underwent a transhyoid resection of a base of tongue carcinoma. Sixty‐four patients (76%) underwent postoperative radioth...

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Bibliographic Details
Published in:Head & neck 2011-08, Vol.33 (8), p.1079-1084
Main Authors: Rodrigo, Juan P., Díaz-Molina, Juan Pablo, Moreno, Carla, Suárez, Carlos
Format: Article
Language:English
Subjects:
Adult
Aged
base of tongue
Biological and medical sciences
cancer
Carcinoma, Squamous Cell - mortality
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - surgery
Cohort Studies
Disease-Free Survival
Female
Humans
Hyoid Bone - surgery
Lymph Nodes - pathology
Lymph Nodes - surgery
Male
Medical sciences
Middle Aged
Multivariate Analysis
Neoplasm Invasiveness - pathology
Neoplasm Recurrence, Local - mortality
Neoplasm Recurrence, Local - pathology
Neoplasm Staging
Otorhinolaryngologic Surgical Procedures - methods
Otorhinolaryngologic Surgical Procedures - mortality
Otorhinolaryngology. Stomatology
Prognosis
Retrospective Studies
surgery
Survival Analysis
Tongue Neoplasms - mortality
Tongue Neoplasms - pathology
Tongue Neoplasms - surgery
transhyoid approach
Treatment Outcome
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Summary:Background The optimal treatment for base of tongue cancer remains unclear, especially in advanced stages. Methods We retrospectively review 84 previously untreated patients that underwent a transhyoid resection of a base of tongue carcinoma. Sixty‐four patients (76%) underwent postoperative radiotherapy. Results Five patients had stage II disease, 6 had stage III, 58 had stage IVA, and 15 had stage IVB. The overall recurrence rate was 68%. Five‐year disease‐specific survival rates by stage were 100%, 67%, 27%, and 8% for stage II to IVB, respectively (p = .0007). Multivariate analysis showed that the presence of lymph node metastases was an independent predictor of reduced disease‐specific survival rates (p = .02). All patients maintained an intelligible voice, and oral alimentation was successfully recovered in 97.5% of them. Conclusions The transhyoid approach allowed adequate resection of base of tongue cancers with low morbidity and acceptable functional results, but the oncologic outcomes in advanced stages are poor. Head Neck, 2011
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.21569