Adherence to lipid-lowering agents among 11,042 patients in clinical practice

Summary Aims:  Dyslipidaemia is a poorly‐controlled condition in clinical practice largely because of poor adherence to medication regimens by patients. This study evaluated the levels of and factors associated with adherence to lipid‐lowering agents in a large Chinese population. Methods:  From a v...

Full description

Saved in:
Bibliographic Details
Published in:International journal of clinical practice (Esher) 2011-07, Vol.65 (7), p.741-748
Main Authors: Wong, M. C. S., Jiang, J. Y., Griffiths, S. M.
Format: Article
Language:English
Subjects:
Adult
Aged
Biological and medical sciences
Clinical medicine
Clinical outcomes
Drug therapy
Female
Fibric Acids - therapeutic use
General aspects
Hong Kong - epidemiology
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Hyperlipidemias - drug therapy
Hyperlipidemias - epidemiology
Hypolipidemic Agents - therapeutic use
Lipids
Male
Medical sciences
Medication Adherence - statistics & numerical data
Middle Aged
Multivariate Analysis
Patient Acceptance of Health Care - statistics & numerical data
Prescription Drugs - therapeutic use
Risk Factors
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Summary Aims:  Dyslipidaemia is a poorly‐controlled condition in clinical practice largely because of poor adherence to medication regimens by patients. This study evaluated the levels of and factors associated with adherence to lipid‐lowering agents in a large Chinese population. Methods:  From a validated clinical database, we included all patients who attended any public, primary care clinics in one large Territory of Hong Kong for medication refill at least twice during the study period January 2004 to June 2007. The major outcome variable was Medication Possession Ratio (MPR), an internationally‐recognised metric to measure drug adherence. The factors associated with optimal drug adherence (MPR ≥ 0.8) were evaluated by multivariate regression analysis. Results:  From 11,042 eligible patients, 90% were adherent. After adjusting for patients’ age, gender, socioeconomic status, service type, district of residence, visit type (new visits vs. follow‐up visits), the number of comorbidities and the drug class (statin vs. fibrates), older patients [aged 50–59 years; adjusted odds ratio (AOR) 1.30, p = 0.009; 60–69 years; AOR 1.53, p 
ISSN:1368-5031
1742-1241
DOI:10.1111/j.1742-1241.2011.02706.x