Primary Cilia: How to Keep the Riff-Raff in the Plasma Membrane

A recent report suggests that plasma membrane proteins are excluded from primary cilia via anchoring to the cortical actin cytoskeleton. These findings challenge the existence of a diffusion barrier at the base of the cilium.

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Bibliographic Details
Published in:Current biology 2011-06, Vol.21 (11), p.R434-R436
Main Authors: Breslow, David K., Nachury, Maxence V.
Format: Article
Language:English
Subjects:
Cell Membrane - metabolism
cilia
Cilia - metabolism
Epithelial Cells - metabolism
membrane proteins
Membrane Proteins - metabolism
microfilaments
Models, Biological
plasma membrane
Protein Transport
Signal Transduction
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Description
Summary:A recent report suggests that plasma membrane proteins are excluded from primary cilia via anchoring to the cortical actin cytoskeleton. These findings challenge the existence of a diffusion barrier at the base of the cilium.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2011.04.039