Sideritis spp.: Uses, chemical composition and pharmacological activities—A review

Sideritis spp. have been traditionally used in Mediterranean area as teas, flavoring agents and for therapeutical purposes because of its anti-inflammatory, digestive, antioxidant and vulnerary properties. This review includes the following topics: botanical aspects, traditional uses, chemical compo...

Full description

Saved in:
Bibliographic Details
Published in:Journal of ethnopharmacology 2011-05, Vol.135 (2), p.209-225
Main Authors: González-Burgos, E., Carretero, M.E., Gómez-Serranillos, M.P.
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Chemical composition
General pharmacology
Humans
Medical sciences
Pharmacognosy. Homeopathy. Health food
Pharmacological activities
Pharmacology. Drug treatments
Plant Extracts - chemistry
Plant Extracts - pharmacology
Sideritis
Sideritis - chemistry
Traditional uses
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Sideritis spp. have been traditionally used in Mediterranean area as teas, flavoring agents and for therapeutical purposes because of its anti-inflammatory, digestive, antioxidant and vulnerary properties. This review includes the following topics: botanical aspects, traditional uses, chemical composition and pharmacological activities as well as future perspectives in research are provided. The genus Sideritis (Lamiaceae) comprises more than 150 perennial and annual vegetal species widely distributed in the Mediterranean area, together with Canary and Madeira islands. It is a controversial botanic genus, with a complex taxonomical classification due to the high number of hybridizations that occur between species; their study requires a deep research experience. Sideritis species have been traditionally used as teas for feeding, flavoring agents and in folk medicine as antiinflammatory, antiulcerative, antimicrobial, vulnerary, antioxidant, antispasmodic, anticonvulsant, analgesic and carminative agents. The chemical components found in Sideritis genus include terpenes, flavonoids, essential oil, iridoids, coumarins, lignanes and sterols, among others. Diterpenes, flavonoids and essential oil occur in almost every species and are the main compounds responsible for the observed in vivo and in vitro pharmacological activities. The aim of this review is to provide a comprehensive overview on the botanical, phytochemical and pharmacological aspects from the genus Sideritis, with the objective of establishing scientific basis that explains its ethnopharmacological use.
ISSN:0378-8741
1872-7573
DOI:10.1016/j.jep.2011.03.014