Attitudinal and demographic predictors of measles, mumps and rubella (MMR) vaccine acceptance: Development and validation of an evidence-based measurement instrument

Abstract Background and objective Parents’ attitudes toward MMR vaccine and measles, mumps and rubella infections relate to their child's MMR status, therefore improving these attitudes is central to improving current suboptimal MMR uptake. However, no study has yet combined evidence-based, com...

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Published in:	Vaccine 2011-02, Vol.29 (8), p.1700-1709
Main Authors:	Brown, Katrina F, Shanley, Ruth, Cowley, Noel A.L, van Wijgerden, Johan, Toff, Penelope, Falconer, Michelle, Ramsay, Mary, Hudson, Michael J, Green, John, Vincent, Charles A, Kroll, J. Simon, Fraser, Graham, Sevdalis, Nick
Format:	Article
Language:	eng
Subjects:	Adolescent Adult Allergy and Immunology Applied microbiology Attitudes attitudes and opinions Autism Biological and medical sciences Child Child, Preschool children Children & youth Cross-Sectional Studies Decision-making Demography England Evidence-Based Medicine Fundamental and applied biological sciences. Psychology Health Knowledge, Attitudes, Practice Humans London Measles Measles - prevention & control Measles-Mumps-Rubella Vaccine - administration & dosage Microbiology MMR Multivariate Analysis Mumps - prevention & control nationalities and ethnic groups Parents Parents & parenting Parents - psychology Patient Acceptance of Health Care - psychology Patient Acceptance of Health Care - statistics & numerical data questionnaires recruitment Reproducibility of Results Rubella - prevention & control Studies Surveys and Questionnaires t-test Vaccination - psychology Vaccination - statistics & numerical data Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects) variance Young Adult
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Summary:	Abstract Background and objective Parents’ attitudes toward MMR vaccine and measles, mumps and rubella infections relate to their child's MMR status, therefore improving these attitudes is central to improving current suboptimal MMR uptake. However, no study has yet combined evidence-based, comprehensive and psychometrically validated assessment of these attitudes with reliable objective MMR status data, in order to identify through multivariate analyses the strongest attitudinal predictors of MMR uptake for interventions to target. The present study fills this lacuna by developing and testing a robust evidence-based MMR attitudes measurement instrument. Design Cross-sectional self-administered postal/telephone questionnaire with objective behavioural outcome. Setting and participants 535 parents of children aged 5–18 in London and north-west England, UK (response rate 18.1%). Recruitment via Primary Care Trust records, age-stratified purposive sample with suboptimally immunised cases oversampled. Main outcome measures Parents’ responses to evidence-based measurement instrument comprising 20 attitude/previous behaviour items (collapsing to 5 scales) and 7 demographic items, and their children's PCT-recorded 5th birthday status for MMR dose 1 (on-time, late or none) and MMR dose 2 (on-time or none). Results The attitudes measurement instrument was psychometrically robust: content valid, and demonstrating good or acceptable internal consistency (Cronbach's alpha = 0.55–0.75 for all scales), test–retest reliability (Pearson's correlation >0.60–0.80, p < 0.01 to
ISSN:	0264-410X 1873-2518