Quality of life in patients with ankylosing spondylitis: relationships with spinal mobility, disease activity and functional status

The aim of this study was to evaluate quality of life (QOL) in patients with ankylosing spondylitis (AS) and to determine the relationships between QOL and clinical variables including spinal mobility, disease activity and functional status. Forty-eight adult patients who fulfilled the modified New...

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Bibliographic Details
Published in:Rheumatology international 2011-05, Vol.31 (5), p.605-610
Main Author: Ozdemir, Oya
Format: Article
Language:English
Subjects:
Activities of Daily Living
Adolescent
Adult
Cost of Illness
Cross-Sectional Studies
Disability Evaluation
Female
Humans
Linear Models
Male
Medicine
Medicine & Public Health
Mental Health
Middle Aged
Original Article
Pain - etiology
Pain Measurement
Predictive Value of Tests
Quality of Life
Range of Motion, Articular
Rheumatology
Severity of Illness Index
Spine - physiopathology
Spondylitis, Ankylosing - complications
Spondylitis, Ankylosing - diagnosis
Spondylitis, Ankylosing - physiopathology
Spondylitis, Ankylosing - psychology
Surveys and Questionnaires
Turkey
Young Adult
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Summary:The aim of this study was to evaluate quality of life (QOL) in patients with ankylosing spondylitis (AS) and to determine the relationships between QOL and clinical variables including spinal mobility, disease activity and functional status. Forty-eight adult patients who fulfilled the modified New York criteria for AS were included in the study. After detailed physical examination, disease-specific instruments: the Bath ankylosing spondylitis disease activity index (BASDAI) and the Bath ankylosing spondylitis functional index (BASFI) were applied. QOL was assessed using short form-36 (SF-36). The mean age of the patients was 37.0 ± 9.7 years and the mean duration of symptoms was 11.7 ± 8.4 years. Most affected domains of SF-36 were bodily pain, vitality, and physical role, respectively. No significant correlations were found between SF-36 subgroup scores and chest expansion, wall–tragus distance, chin–sternum distance, and floor–finger tip distance. Only modified Schober correlated with two SF-36 domains: physical role and bodily pain. BASDAI and BASFI scores had significant negative correlations with all SF-36 domains except for general health. Identification of QOL in patients with AS is very important in evaluation of illness-related sufferings and development of new management strategies.
ISSN:0172-8172
1437-160X
DOI:10.1007/s00296-009-1328-2