Non-invasive screening of HLA-DPA1 and HLA-DPB1 alleles for persistent hepatitis B virus infection: Susceptibility for vertical transmission and toward a personalized approach for vaccination and treatment

Polymorphisms in the major histocompatibility complex (MHC) and non-MHC genes were recently reported to be associated with persistent hepatitis B virus (HBV) infection and host response to hepatitis B vaccine in Asian populations. We aimed to confirm the associations in Chinese population and develo...

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Bibliographic Details

Published in:	Clinica chimica acta 2011-05, Vol.412 (11-12), p.952-957
Main Authors:	Lau, Kin-Chong, Lam, Ching-Wan, Law, Chun-Yiu, Lai, Sik-To, Tsang, Tak-Yin, Siu, Carol Wai-Kwan, To, Wing-Kin, Leung, Ka-Fai, Mak, Chloe Miu, Poon, Wing-Tat, Chan, Paul Kay-Sheung, Chan, Yan-Wo
Format:	Article
Language:	eng
Subjects:	Adult Aged Aged, 80 and over Alleles Chronic hepatitis B Female Genetic Loci - genetics Genetic Testing - methods Hepatitis B virus - pathogenicity Hepatitis B, Chronic - genetics Hepatitis B, Chronic - prevention & control Hepatitis B, Chronic - therapy Hepatitis B, Chronic - transmission HLA-DP alpha-Chains - genetics HLA-DP beta-Chains - genetics Host genetic risk factor Humans Infectious Disease Transmission, Vertical Male Middle Aged Precision Medicine - methods Salivary diagnostic Vaccination - methods Young Adult
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