Bioactive Compounds from the Scale Insect Pathogenic Fungus Conoideocrella tenuis BCC 18627

A new cyclohexadepsipeptide, conoideocrellide A (1), its linear derivatives, conoideocrellides B−D (2−4), three new hopane triterpenoids (5−7), two new bioxanthracenes (9 and 10), and a new isocoumarin glycoside (13) were isolated from the scale insect pathogenic fungus Conoideocrella tenuis BCC 186...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 2011-04, Vol.74 (4), p.782-789
Main Authors: Isaka, Masahiko, Palasarn, Somporn, Supothina, Sumalee, Komwijit, Somjit, Luangsa-ard, J. Jennifer
Format: Article
Language:English
Subjects:
Animals
Anthracenes - chemistry
Anthracenes - isolation & purification
Anthracenes - pharmacology
Antineoplastic Agents - chemistry
Antineoplastic Agents - isolation & purification
Antineoplastic Agents - pharmacology
Biological and medical sciences
Cercopithecus aethiops
Depsipeptides - chemistry
Depsipeptides - isolation & purification
Depsipeptides - pharmacology
Drug Screening Assays, Antitumor
General pharmacology
Glycosides - chemistry
Glycosides - isolation & purification
Glycosides - pharmacology
Hemiptera - microbiology
Herpesvirus 1, Human - drug effects
Hypocreales - chemistry
Isocoumarins - chemistry
Isocoumarins - isolation & purification
Isocoumarins - pharmacology
Medical sciences
Molecular Structure
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plasmodium falciparum - drug effects
Triterpenes - chemistry
Triterpenes - isolation & purification
Triterpenes - pharmacology
Vero Cells
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Summary:A new cyclohexadepsipeptide, conoideocrellide A (1), its linear derivatives, conoideocrellides B−D (2−4), three new hopane triterpenoids (5−7), two new bioxanthracenes (9 and 10), and a new isocoumarin glycoside (13) were isolated from the scale insect pathogenic fungus Conoideocrella tenuis BCC 18627. Biological activities of the new compounds were evaluated.
ISSN:0163-3864
1520-6025
DOI:10.1021/np100849x