Decision tree analysis of treatment strategies for mild and moderate cases of clinical mastitis occurring in early lactation

The objective of this study was to develop a decision tree to evaluate the economic impact of different durations of intramammary treatment for the first case of mild or moderate clinical mastitis (CM) occurring in early lactation with various scenarios of pathogen distributions and use of on-farm c...

Full description

Saved in:
Bibliographic Details
Published in:Journal of dairy science 2011-04, Vol.94 (4), p.1873-1892
Main Authors: Pinzón-Sánchez, C., Cabrera, V.E., Ruegg, P.L.
Format: Article
Language:English
Subjects:
Animal productions
Animals
Anti-Infective Agents - administration & dosage
Anti-Infective Agents - therapeutic use
antimicrobial agents
Biological and medical sciences
Cattle
cows
Dairying - economics
Dairying - methods
decision support systems
decision tree model
Decision Trees
disease transmission
Drug Administration Schedule - veterinary
early lactation
economic impact
Female
Food industries
Fundamental and applied biological sciences. Psychology
labor
Lactation - physiology
Mammary Glands, Animal
mastitis
Mastitis, Bovine - drug therapy
Mastitis, Bovine - economics
Mastitis, Bovine - microbiology
milk
Milk - economics
Milk - microbiology
Milk and cheese industries. Ice creams
milk production
Models, Economic
on-farm culture
pathogen distribution
pathogens
Probability
Severity of Illness Index
Staphylococcus aureus
Staphylococcus aureus - isolation & purification
Terrestrial animal productions
therapeutics
Time Factors
Treatment Outcome
trees
Vertebrates
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The objective of this study was to develop a decision tree to evaluate the economic impact of different durations of intramammary treatment for the first case of mild or moderate clinical mastitis (CM) occurring in early lactation with various scenarios of pathogen distributions and use of on-farm culture. The tree included 2 decision and 3 probability events. The first decision evaluated use of on-farm culture (OFC; 2 programs using OFC and 1 not using OFC) and the second decision evaluated treatment strategies (no intramammary antimicrobials or antimicrobials administered for 2, 5, or 8 d). The tree included probabilities for the distribution of etiologies (gram-positive, gram-negative, or no growth), bacteriological cure, and recurrence. The economic consequences of mastitis included costs of diagnosis and initial treatment, additional treatments, labor, discarded milk, milk production losses due to clinical and subclinical mastitis, culling, and transmission of infection to other cows (only for CM caused by Staphylococcus aureus). Pathogen-specific estimates for bacteriological cure and milk losses were used. The economically optimal path for several scenarios was determined by comparison of expected monetary values. For most scenarios, the optimal economic strategy was to treat CM caused by gram-positive pathogens for 2 d and to avoid antimicrobials for CM cases caused by gram-negative pathogens or when no pathogen was recovered. Use of extended intramammary antimicrobial therapy (5 or 8 d) resulted in the least expected monetary values.
ISSN:0022-0302
1525-3198
DOI:10.3168/jds.2010-3930