Correlation of serum trace elements and melatonin levels to radiological, biochemical, and histological assessment of degeneration in patients with intervertebral disc herniation

The aim of our study was to assess the blood concentrations of some trace elements and melatonin (MLT) in patients with intervertebral disc herniation (IDH) and to investigate the interaction of histological and biochemical degeneration findings with aging. The present study was carried out on 13 su...

Full description

Saved in:
Bibliographic Details
Published in:Biological trace element research 2006-02, Vol.109 (2), p.123-134
Main Authors: Turgut, Mehmet, Yenisey, Cigdem, Akyüz, Orhan, Ozsunar, Yelda, Erkus, Muhan, Biçakçi, Tuncay
Format: Article
Language:English
Subjects:
Adult
Age
Aged
Aging
Biochemistry
Blood
Brain
Calcification
Calcinosis
Collagen - analysis
Computed tomography
Data Interpretation, Statistical
Data processing
Female
Geriatrics
Histology
Humans
Hydroxyproline
Hydroxyproline - analysis
Intervertebral Disc - chemistry
Intervertebral Disc - pathology
Intervertebral Disc Displacement - blood
Intervertebral Disc Displacement - pathology
Intervertebral discs
Lumbar Vertebrae - pathology
Magnesium
Magnesium - blood
Magnetic Resonance Imaging
Male
Medical research
Melatonin
Melatonin - blood
Middle Aged
Neurodegeneration
Nighttime
Pineal gland
Pineal Gland - diagnostic imaging
Spectrophotometry, Atomic
Spine
Spine (lumbar)
Tomography, X-Ray Computed
Trace elements
Zinc
Zinc - blood
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c397t-4771d4c5e6b81babbe11e3ed66c220212edccef4d3cac800d5be6318476d9783
cites
container_end_page 134
container_issue 2
container_start_page 123
container_title Biological trace element research
container_volume 109
creator Turgut, Mehmet
Yenisey, Cigdem
Akyüz, Orhan
Ozsunar, Yelda
Erkus, Muhan
Biçakçi, Tuncay
description The aim of our study was to assess the blood concentrations of some trace elements and melatonin (MLT) in patients with intervertebral disc herniation (IDH) and to investigate the interaction of histological and biochemical degeneration findings with aging. The present study was carried out on 13 subjects (8 women and 5 men) diagnosed with IDH. They were divided into three groups according to their ages. Nighttime serum MLT, zinc (Zn), and magnesium (Mg) levels were determined in all patients. In addition, computed tomography (CT) scan of the brain and magnetic resonance imaging examination of the lumbar spine were obtained in this study. The Zn level and Zn/Mg ratio showed a decline in patients with IDH with aging, whereas the serum Mg level and tissue hydroxyproline content increased. A positive correlation between serum Zn and MLT concentrations was found (r=0.104, p=0.734). In addition, there was a positive correlation between serum Zn level and Zn/Mg ratio (r=0.835 and p
doi_str_mv 10.1385/BTER:109:2:123
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_856760252</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>856760252</sourcerecordid><originalsourceid>FETCH-LOGICAL-c397t-4771d4c5e6b81babbe11e3ed66c220212edccef4d3cac800d5be6318476d9783</originalsourceid><addsrcrecordid>eNp9kUuPFCEUhYnROO3o1qUhLnRjjbwKqno3dsZHMomJ6T2h4PY0E6pogRrj3_IXSnW3MXHhCi585xzIQeglJVeUd-37D9ubb2tK-jVbU8YfoRVt274hipHHaEWo5I3oO3GBnuV8TwhVrOdP0QWVQghC2Ar92sSUIJji44TjDmdI84hLMhYwBBhhKhmbyeFxgeLkJxzgAULGJeJknI8h3nlrwjs8-Gj3MJ6GRbL3ufy5xiZnyHnxW2Ic3MEE6RRbPQ91d4z64cu-HhRID5AKDKlKnc8W7yFN_sg_R092JmR4cV4v0fbjzXbzubn9-unL5vq2sbxXpRFKUSdsC3Lo6GCGASgFDk5KyxhhlIGzFnbCcWtsR4hrB5CcdkJJ16uOX6K3J9tDit9nyEWP9R0Qgpkgzll3rVSSsJZV8s1_SUUU5S1XFXz9D3gf5zTVT2hWg6nqj25XJ8immHOCnT4kP5r0U1Oil8710nkdes107bwKXp1d52EE9xc_l8x_AyyprE0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>218417952</pqid></control><display><type>article</type><title>Correlation of serum trace elements and melatonin levels to radiological, biochemical, and histological assessment of degeneration in patients with intervertebral disc herniation</title><source>Springer Link</source><creator>Turgut, Mehmet ; Yenisey, Cigdem ; Akyüz, Orhan ; Ozsunar, Yelda ; Erkus, Muhan ; Biçakçi, Tuncay</creator><creatorcontrib>Turgut, Mehmet ; Yenisey, Cigdem ; Akyüz, Orhan ; Ozsunar, Yelda ; Erkus, Muhan ; Biçakçi, Tuncay</creatorcontrib><description>The aim of our study was to assess the blood concentrations of some trace elements and melatonin (MLT) in patients with intervertebral disc herniation (IDH) and to investigate the interaction of histological and biochemical degeneration findings with aging. The present study was carried out on 13 subjects (8 women and 5 men) diagnosed with IDH. They were divided into three groups according to their ages. Nighttime serum MLT, zinc (Zn), and magnesium (Mg) levels were determined in all patients. In addition, computed tomography (CT) scan of the brain and magnetic resonance imaging examination of the lumbar spine were obtained in this study. The Zn level and Zn/Mg ratio showed a decline in patients with IDH with aging, whereas the serum Mg level and tissue hydroxyproline content increased. A positive correlation between serum Zn and MLT concentrations was found (r=0.104, p=0.734). In addition, there was a positive correlation between serum Zn level and Zn/Mg ratio (r=0.835 and p&lt;0.01), and a negative correlation between serum Mg level and Zn/Mg ratio (r=-0.571, p&lt;0.05). On CT study, both volume percentage of calcified pineal gland and density of calcification were found to increase progressively with advancing age. The results of semiquantitative evaluation of disc tissues of patients with IDH for histological degeneration findings showed that 66.7% of discs treated had slight degeneration in younger age group, but 75.0% and 100% of discs had moderate or marked degeneration in older age groups. Our data indicated that there is a close relationship between MLT and Zn or Mg levels in the serum samples of patients with IDH, and the levels of these elements might be affected by the presence of degeneration process and serum MLT level, or vice versa.</description><identifier>ISSN: 0163-4984</identifier><identifier>EISSN: 1559-0720</identifier><identifier>EISSN: 0163-4984</identifier><identifier>DOI: 10.1385/BTER:109:2:123</identifier><identifier>PMID: 16444002</identifier><language>eng</language><publisher>United States: Springer Nature B.V</publisher><subject>Adult ; Age ; Aged ; Aging ; Biochemistry ; Blood ; Brain ; Calcification ; Calcinosis ; Collagen - analysis ; Computed tomography ; Data Interpretation, Statistical ; Data processing ; Female ; Geriatrics ; Histology ; Humans ; Hydroxyproline ; Hydroxyproline - analysis ; Intervertebral Disc - chemistry ; Intervertebral Disc - pathology ; Intervertebral Disc Displacement - blood ; Intervertebral Disc Displacement - pathology ; Intervertebral discs ; Lumbar Vertebrae - pathology ; Magnesium ; Magnesium - blood ; Magnetic Resonance Imaging ; Male ; Medical research ; Melatonin ; Melatonin - blood ; Middle Aged ; Neurodegeneration ; Nighttime ; Pineal gland ; Pineal Gland - diagnostic imaging ; Spectrophotometry, Atomic ; Spine ; Spine (lumbar) ; Tomography, X-Ray Computed ; Trace elements ; Zinc ; Zinc - blood</subject><ispartof>Biological trace element research, 2006-02, Vol.109 (2), p.123-134</ispartof><rights>Humana Press Inc. 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c397t-4771d4c5e6b81babbe11e3ed66c220212edccef4d3cac800d5be6318476d9783</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16444002$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Turgut, Mehmet</creatorcontrib><creatorcontrib>Yenisey, Cigdem</creatorcontrib><creatorcontrib>Akyüz, Orhan</creatorcontrib><creatorcontrib>Ozsunar, Yelda</creatorcontrib><creatorcontrib>Erkus, Muhan</creatorcontrib><creatorcontrib>Biçakçi, Tuncay</creatorcontrib><title>Correlation of serum trace elements and melatonin levels to radiological, biochemical, and histological assessment of degeneration in patients with intervertebral disc herniation</title><title>Biological trace element research</title><addtitle>Biol Trace Elem Res</addtitle><description>The aim of our study was to assess the blood concentrations of some trace elements and melatonin (MLT) in patients with intervertebral disc herniation (IDH) and to investigate the interaction of histological and biochemical degeneration findings with aging. The present study was carried out on 13 subjects (8 women and 5 men) diagnosed with IDH. They were divided into three groups according to their ages. Nighttime serum MLT, zinc (Zn), and magnesium (Mg) levels were determined in all patients. In addition, computed tomography (CT) scan of the brain and magnetic resonance imaging examination of the lumbar spine were obtained in this study. The Zn level and Zn/Mg ratio showed a decline in patients with IDH with aging, whereas the serum Mg level and tissue hydroxyproline content increased. A positive correlation between serum Zn and MLT concentrations was found (r=0.104, p=0.734). In addition, there was a positive correlation between serum Zn level and Zn/Mg ratio (r=0.835 and p&lt;0.01), and a negative correlation between serum Mg level and Zn/Mg ratio (r=-0.571, p&lt;0.05). On CT study, both volume percentage of calcified pineal gland and density of calcification were found to increase progressively with advancing age. The results of semiquantitative evaluation of disc tissues of patients with IDH for histological degeneration findings showed that 66.7% of discs treated had slight degeneration in younger age group, but 75.0% and 100% of discs had moderate or marked degeneration in older age groups. Our data indicated that there is a close relationship between MLT and Zn or Mg levels in the serum samples of patients with IDH, and the levels of these elements might be affected by the presence of degeneration process and serum MLT level, or vice versa.</description><subject>Adult</subject><subject>Age</subject><subject>Aged</subject><subject>Aging</subject><subject>Biochemistry</subject><subject>Blood</subject><subject>Brain</subject><subject>Calcification</subject><subject>Calcinosis</subject><subject>Collagen - analysis</subject><subject>Computed tomography</subject><subject>Data Interpretation, Statistical</subject><subject>Data processing</subject><subject>Female</subject><subject>Geriatrics</subject><subject>Histology</subject><subject>Humans</subject><subject>Hydroxyproline</subject><subject>Hydroxyproline - analysis</subject><subject>Intervertebral Disc - chemistry</subject><subject>Intervertebral Disc - pathology</subject><subject>Intervertebral Disc Displacement - blood</subject><subject>Intervertebral Disc Displacement - pathology</subject><subject>Intervertebral discs</subject><subject>Lumbar Vertebrae - pathology</subject><subject>Magnesium</subject><subject>Magnesium - blood</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Medical research</subject><subject>Melatonin</subject><subject>Melatonin - blood</subject><subject>Middle Aged</subject><subject>Neurodegeneration</subject><subject>Nighttime</subject><subject>Pineal gland</subject><subject>Pineal Gland - diagnostic imaging</subject><subject>Spectrophotometry, Atomic</subject><subject>Spine</subject><subject>Spine (lumbar)</subject><subject>Tomography, X-Ray Computed</subject><subject>Trace elements</subject><subject>Zinc</subject><subject>Zinc - blood</subject><issn>0163-4984</issn><issn>1559-0720</issn><issn>0163-4984</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><recordid>eNp9kUuPFCEUhYnROO3o1qUhLnRjjbwKqno3dsZHMomJ6T2h4PY0E6pogRrj3_IXSnW3MXHhCi585xzIQeglJVeUd-37D9ubb2tK-jVbU8YfoRVt274hipHHaEWo5I3oO3GBnuV8TwhVrOdP0QWVQghC2Ar92sSUIJji44TjDmdI84hLMhYwBBhhKhmbyeFxgeLkJxzgAULGJeJknI8h3nlrwjs8-Gj3MJ6GRbL3ufy5xiZnyHnxW2Ic3MEE6RRbPQ91d4z64cu-HhRID5AKDKlKnc8W7yFN_sg_R092JmR4cV4v0fbjzXbzubn9-unL5vq2sbxXpRFKUSdsC3Lo6GCGASgFDk5KyxhhlIGzFnbCcWtsR4hrB5CcdkJJ16uOX6K3J9tDit9nyEWP9R0Qgpkgzll3rVSSsJZV8s1_SUUU5S1XFXz9D3gf5zTVT2hWg6nqj25XJ8immHOCnT4kP5r0U1Oil8710nkdes107bwKXp1d52EE9xc_l8x_AyyprE0</recordid><startdate>20060201</startdate><enddate>20060201</enddate><creator>Turgut, Mehmet</creator><creator>Yenisey, Cigdem</creator><creator>Akyüz, Orhan</creator><creator>Ozsunar, Yelda</creator><creator>Erkus, Muhan</creator><creator>Biçakçi, Tuncay</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QH</scope><scope>7QP</scope><scope>7TN</scope><scope>7U7</scope><scope>7UA</scope><scope>7X7</scope><scope>7XB</scope><scope>88A</scope><scope>88E</scope><scope>88I</scope><scope>8AO</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>BKSAR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>F1W</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H97</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>L.G</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M2P</scope><scope>M7P</scope><scope>PCBAR</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20060201</creationdate><title>Correlation of serum trace elements and melatonin levels to radiological, biochemical, and histological assessment of degeneration in patients with intervertebral disc herniation</title><author>Turgut, Mehmet ; Yenisey, Cigdem ; Akyüz, Orhan ; Ozsunar, Yelda ; Erkus, Muhan ; Biçakçi, Tuncay</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c397t-4771d4c5e6b81babbe11e3ed66c220212edccef4d3cac800d5be6318476d9783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Age</topic><topic>Aged</topic><topic>Aging</topic><topic>Biochemistry</topic><topic>Blood</topic><topic>Brain</topic><topic>Calcification</topic><topic>Calcinosis</topic><topic>Collagen - analysis</topic><topic>Computed tomography</topic><topic>Data Interpretation, Statistical</topic><topic>Data processing</topic><topic>Female</topic><topic>Geriatrics</topic><topic>Histology</topic><topic>Humans</topic><topic>Hydroxyproline</topic><topic>Hydroxyproline - analysis</topic><topic>Intervertebral Disc - chemistry</topic><topic>Intervertebral Disc - pathology</topic><topic>Intervertebral Disc Displacement - blood</topic><topic>Intervertebral Disc Displacement - pathology</topic><topic>Intervertebral discs</topic><topic>Lumbar Vertebrae - pathology</topic><topic>Magnesium</topic><topic>Magnesium - blood</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Medical research</topic><topic>Melatonin</topic><topic>Melatonin - blood</topic><topic>Middle Aged</topic><topic>Neurodegeneration</topic><topic>Nighttime</topic><topic>Pineal gland</topic><topic>Pineal Gland - diagnostic imaging</topic><topic>Spectrophotometry, Atomic</topic><topic>Spine</topic><topic>Spine (lumbar)</topic><topic>Tomography, X-Ray Computed</topic><topic>Trace elements</topic><topic>Zinc</topic><topic>Zinc - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Turgut, Mehmet</creatorcontrib><creatorcontrib>Yenisey, Cigdem</creatorcontrib><creatorcontrib>Akyüz, Orhan</creatorcontrib><creatorcontrib>Ozsunar, Yelda</creatorcontrib><creatorcontrib>Erkus, Muhan</creatorcontrib><creatorcontrib>Biçakçi, Tuncay</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Aqualine</collection><collection>Calcium &amp; Calcified Tissue Abstracts</collection><collection>Oceanic Abstracts</collection><collection>Toxicology Abstracts</collection><collection>Water Resources Abstracts</collection><collection>Health &amp; Medical Collection (ProQuest Medical &amp; Health Databases)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Biology Database (Alumni Edition)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Science Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>ProQuest Natural Science Collection</collection><collection>Earth, Atmospheric &amp; Aquatic Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>ASFA: Aquatic Sciences and Fisheries Abstracts</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) 3: Aquatic Pollution &amp; Environmental Quality</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Aquatic Science &amp; Fisheries Abstracts (ASFA) Professional</collection><collection>Biological Sciences</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>ProQuest Science Journals</collection><collection>Biological Science Database</collection><collection>Earth, Atmospheric &amp; Aquatic Science Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Biological trace element research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Turgut, Mehmet</au><au>Yenisey, Cigdem</au><au>Akyüz, Orhan</au><au>Ozsunar, Yelda</au><au>Erkus, Muhan</au><au>Biçakçi, Tuncay</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Correlation of serum trace elements and melatonin levels to radiological, biochemical, and histological assessment of degeneration in patients with intervertebral disc herniation</atitle><jtitle>Biological trace element research</jtitle><addtitle>Biol Trace Elem Res</addtitle><date>2006-02-01</date><risdate>2006</risdate><volume>109</volume><issue>2</issue><spage>123</spage><epage>134</epage><pages>123-134</pages><issn>0163-4984</issn><eissn>1559-0720</eissn><eissn>0163-4984</eissn><notes>ObjectType-Article-1</notes><notes>SourceType-Scholarly Journals-1</notes><notes>ObjectType-Feature-2</notes><notes>content type line 23</notes><notes>ObjectType-Article-2</notes><notes>ObjectType-Feature-1</notes><abstract>The aim of our study was to assess the blood concentrations of some trace elements and melatonin (MLT) in patients with intervertebral disc herniation (IDH) and to investigate the interaction of histological and biochemical degeneration findings with aging. The present study was carried out on 13 subjects (8 women and 5 men) diagnosed with IDH. They were divided into three groups according to their ages. Nighttime serum MLT, zinc (Zn), and magnesium (Mg) levels were determined in all patients. In addition, computed tomography (CT) scan of the brain and magnetic resonance imaging examination of the lumbar spine were obtained in this study. The Zn level and Zn/Mg ratio showed a decline in patients with IDH with aging, whereas the serum Mg level and tissue hydroxyproline content increased. A positive correlation between serum Zn and MLT concentrations was found (r=0.104, p=0.734). In addition, there was a positive correlation between serum Zn level and Zn/Mg ratio (r=0.835 and p&lt;0.01), and a negative correlation between serum Mg level and Zn/Mg ratio (r=-0.571, p&lt;0.05). On CT study, both volume percentage of calcified pineal gland and density of calcification were found to increase progressively with advancing age. The results of semiquantitative evaluation of disc tissues of patients with IDH for histological degeneration findings showed that 66.7% of discs treated had slight degeneration in younger age group, but 75.0% and 100% of discs had moderate or marked degeneration in older age groups. Our data indicated that there is a close relationship between MLT and Zn or Mg levels in the serum samples of patients with IDH, and the levels of these elements might be affected by the presence of degeneration process and serum MLT level, or vice versa.</abstract><cop>United States</cop><pub>Springer Nature B.V</pub><pmid>16444002</pmid><doi>10.1385/BTER:109:2:123</doi><tpages>12</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0163-4984
ispartof Biological trace element research, 2006-02, Vol.109 (2), p.123-134
issn 0163-4984
1559-0720
0163-4984
language eng
recordid cdi_proquest_miscellaneous_856760252
source Springer Link
subjects Adult
Age
Aged
Aging
Biochemistry
Blood
Brain
Calcification
Calcinosis
Collagen - analysis
Computed tomography
Data Interpretation, Statistical
Data processing
Female
Geriatrics
Histology
Humans
Hydroxyproline
Hydroxyproline - analysis
Intervertebral Disc - chemistry
Intervertebral Disc - pathology
Intervertebral Disc Displacement - blood
Intervertebral Disc Displacement - pathology
Intervertebral discs
Lumbar Vertebrae - pathology
Magnesium
Magnesium - blood
Magnetic Resonance Imaging
Male
Medical research
Melatonin
Melatonin - blood
Middle Aged
Neurodegeneration
Nighttime
Pineal gland
Pineal Gland - diagnostic imaging
Spectrophotometry, Atomic
Spine
Spine (lumbar)
Tomography, X-Ray Computed
Trace elements
Zinc
Zinc - blood
title Correlation of serum trace elements and melatonin levels to radiological, biochemical, and histological assessment of degeneration in patients with intervertebral disc herniation
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-09-22T01%3A43%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Correlation%20of%20serum%20trace%20elements%20and%20melatonin%20levels%20to%20radiological,%20biochemical,%20and%20histological%20assessment%20of%20degeneration%20in%20patients%20with%20intervertebral%20disc%20herniation&rft.jtitle=Biological%20trace%20element%20research&rft.au=Turgut,%20Mehmet&rft.date=2006-02-01&rft.volume=109&rft.issue=2&rft.spage=123&rft.epage=134&rft.pages=123-134&rft.issn=0163-4984&rft.eissn=1559-0720&rft_id=info:doi/10.1385/BTER:109:2:123&rft_dat=%3Cproquest_cross%3E856760252%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c397t-4771d4c5e6b81babbe11e3ed66c220212edccef4d3cac800d5be6318476d9783%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=218417952&rft_id=info:pmid/16444002&rfr_iscdi=true