Electrn microscopic observations on virus-like particles associated with SH antigen

The structural aspects of SH antigen-containing particles were investigated. These studies confirmed the existence of a large spherical particle (ca. 43 nm) and smaller (ca. 20 nm) rod- and sphere-shaped particles. The large particle consists of an outer and inner membrane and a core of "nuclei...

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Bibliographic Details
Published in:Journal of virology 1970-11, Vol.6 (5), p.685-689
Main Authors: Jokelainen, P T, Krohn, K, Prince, A M, Finlayson, N D
Format: Article
Language:English
Subjects:
Acute Disease
Antigens
Carrier State - immunology
Carrier State - microbiology
Chronic Disease
Hepatitis B - immunology
Hepatitis B - microbiology
Hepatitis B virus - immunology
Hepatitis B virus - isolation & purification
Humans
Microscopy, Electron
Phosphotungstic Acid
Potassium Permanganate
Staining and Labeling
Uranium
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Summary:The structural aspects of SH antigen-containing particles were investigated. These studies confirmed the existence of a large spherical particle (ca. 43 nm) and smaller (ca. 20 nm) rod- and sphere-shaped particles. The large particle consists of an outer and inner membrane and a core of "nucleic acid" as seen by positive staining techniques. The outer membrane of the large particle appears to be similar to that of the 20-nm diameter spheres and rods known to possess the SH antigen.
ISSN:0022-538X
1098-5514
DOI:10.1128/jvi.6.5.685-689.1970