Incomplete right bundle branch block: a novel electrocardiographic marker for lone atrial fibrillation

P-wave morphology and PR interval have both been previously associated with atrial fibrillation (AF). We hypothesized that incomplete right bundle branch block (IRBBB) would be associated with early-onset lone AF. We conducted a case-control study comparing electrocardiographic (ECG) markers from pa...

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Bibliographic Details
Published in:Europace (London, England) England), 2011-02, Vol.13 (2), p.182-187
Main Authors: Nielsen, Jonas Bille, Olesen, Morten Salling, Tangø, Mogens, Haunsø, Stig, Holst, Anders Gaarsdal, Svendsen, Jesper Hastrup
Format: Article
Language:English
Subjects:
Adult
Atrial Fibrillation - diagnosis
Atrial Fibrillation - physiopathology
Bundle of His - physiopathology
Bundle-Branch Block - physiopathology
Case-Control Studies
Electrocardiography
Female
Heart Rate - physiology
Heart Ventricles - physiopathology
Humans
Incidence
Male
Multivariate Analysis
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Summary:P-wave morphology and PR interval have both been previously associated with atrial fibrillation (AF). We hypothesized that incomplete right bundle branch block (IRBBB) would be associated with early-onset lone AF. We conducted a case-control study comparing electrocardiographic (ECG) markers from patients with early-onset lone AF and from a healthy control population. We included 187 patients with early-onset lone AF and 383 healthy controls. Sixty-two lone AF patients were excluded from the study because of AF at the time of enrolment or because of the use of antiarrhythmic drugs. For the remaining 125 patients with paroxysmal or persistent lone AF (84% males, mean age 37), controls were matched on a 1:1 basis on the parameters gender and age. A significantly higher proportion of the lone AF population had an IRBBB compared with the subjects in the control group (33.6 vs. 10.4%; P
ISSN:1099-5129
1532-2092
DOI:10.1093/europace/euq436