Carcinoma of the bladder T3NxMo treated by preoperative irradiation followed by cystectomy

Eighty-nine patients with bladder cancer T3NxMo have been treated by preoperative external irradiation (4000 rads in 4 weeks) followed by cystectomy. Five-year survival is 50%. Of patients with T-reduction (T3 becomes P0, P1, or P2) the 5-year survival is 70%. Treatment mortality has been reduced to...

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Bibliographic Details
Published in:Cancer 1975-08, Vol.36 (2), p.718-722
Main Author: van der Werf-Messing, B H
Format: Article
Language:English
Subjects:
Adult
Aged
Biopsy
Female
Humans
Lymphatic Metastasis
Male
Palpation
Preoperative Care
Radiography
Urinary Bladder - pathology
Urinary Bladder Neoplasms - diagnostic imaging
Urinary Bladder Neoplasms - mortality
Urinary Bladder Neoplasms - pathology
Urinary Bladder Neoplasms - surgery
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Summary:Eighty-nine patients with bladder cancer T3NxMo have been treated by preoperative external irradiation (4000 rads in 4 weeks) followed by cystectomy. Five-year survival is 50%. Of patients with T-reduction (T3 becomes P0, P1, or P2) the 5-year survival is 70%. Treatment mortality has been reduced to 3% during the last 2 years. T-reduction cannot be predicted by histologic grade. A second staging by palpation under general anesthesia ("T" 4000) is reliable when T-reduction is felt; however, fibrosis can simulate a persisting T3 mass.
ISSN:0008-543X
1097-0142