Generalized melanosis complicating disseminated malignant melanoma in pregnancy: A case report

A case of generalized melanosis complicating disseminated malignant melanoma in pregnancy is described. Four features of this case, unique in combination, are discussed. First, generalized melanosis is a rare complication in macrophages of skin and other areas. Secondly, extensive bone lesions in th...

Full description

Saved in:
Bibliographic Details
Published in:Cancer 1975-05, Vol.35 (5), p.1459-1464
Main Authors: Holcomb, Barry W., Thigpen, J. Tate, Puckett, James F., Morrison, Francis S.
Format: Article
Language:English
Subjects:
Adult
Female
Humans
Melanoma - complications
Melanosis - etiology
Neoplasm Metastasis
Placenta
Pregnancy
Pregnancy Complications
Skin Neoplasms - complications
Skull Neoplasms - pathology
Spinal Neoplasms - pathology
Citations: Items that this one cites
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A case of generalized melanosis complicating disseminated malignant melanoma in pregnancy is described. Four features of this case, unique in combination, are discussed. First, generalized melanosis is a rare complication in macrophages of skin and other areas. Secondly, extensive bone lesions in the absence of roentgenographic changes are an uncommon occurrence. Thirdly, pregnancy probably has little effect on the course of melanoma, as illustrated by this case and a review of the literature. Finally, placental metastases may be more common than generally thought, yet may have little significance to the fetus.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197505)35:5<1459::AID-CNCR2820350534>3.0.CO;2-9