Impact of Chronic Pre-Treatment of Statins on the Level of Systemic Inflammation and Myocardial Perfusion in Patients Undergoing Primary Angioplasty

Statins have many favorable pleiotropic effects beyond their lipid-lowering properties. The aim of this study was to evaluate the impact of long-term statin pretreatment on the level of systemic inflammation and myocardial perfusion in patients with acute myocardial infarctions. This was a retrospec...

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Bibliographic Details
Published in:The American journal of cardiology 2011-01, Vol.107 (2), p.179-185
Main Authors: Oduncu, Vecih, MD, Tanalp, Ali Cevat, MD, Erkol, Ayhan, MD, Sırma, Dicle, MD, Dündar, Cihan, MD, Akgün, Taylan, MD, Türkyılmaz, Erdem, MD, Kılıçgedik, Alev, MD, Gözübüyük, Gökhan, MD, Tigen, Kürşat, MD, Izgi, Akın, MD, Kırma, Cevat, MD
Format: Article
Language:English
Subjects:
Aged
Angioplasty
Angioplasty, Balloon, Coronary
Biological and medical sciences
C-Reactive Protein - metabolism
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular disease
Coronary Angiography
Coronary Circulation - drug effects
Diseases of the cardiovascular system
Electrocardiography
Female
Follow-Up Studies
Heart attacks
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Inflammation - blood
Lipids
Male
Medical sciences
Medical treatment
Middle Aged
Myocardial Ischemia - blood
Myocardial Ischemia - drug therapy
Myocardial Ischemia - physiopathology
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Retrospective Studies
Statins
Time Factors
Treatment Outcome
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Description
Summary:Statins have many favorable pleiotropic effects beyond their lipid-lowering properties. The aim of this study was to evaluate the impact of long-term statin pretreatment on the level of systemic inflammation and myocardial perfusion in patients with acute myocardial infarctions. This was a retrospective study of 1,617 patients with acute ST-segment elevation myocardial infarctions who underwent primary percutaneous coronary intervention
ISSN:0002-9149
1879-1913
DOI:10.1016/j.amjcard.2010.09.008