Abdominal obesity, insulin resistance, and metabolic syndrome in a southern European population

Background: Our objective was to investigate the relationship between abdominal obesity (AO), as measured by waist circumference (WC), insulin resistance (IR), and components of the metabolic syndrome (MS). Methods: A cross-sectional study was carried out with 283 subjects (130 males and 153 females...

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Bibliographic Details
Published in:European journal of internal medicine 2003-03, Vol.14 (2), p.101-106
Main Authors: Ascaso, Juan F., Romero, Pedro, Real, José T., Lorente, Rosario I., Martı&#x0301, nez-Valls, José, Carmena, Rafael
Format: Article
Language:English
Subjects:
Abdominal obesity
HOMA-IR
Insulin resistance
Metabolic syndrome
Obesity
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Summary:Background: Our objective was to investigate the relationship between abdominal obesity (AO), as measured by waist circumference (WC), insulin resistance (IR), and components of the metabolic syndrome (MS). Methods: A cross-sectional study was carried out with 283 subjects (130 males and 153 females aged 25–65 years) from a primary care outpatient clinic in Valencia (Spain) over a period of 1 year. Body mass index (BMI), waist circumference (WC), blood pressure (BP), total cholesterol, triglycerides, HDL-C, glucose, and insulin were measured by standard methods. IR was defined as HOMA-IR equal to or greater than 3.8. Results: The prevalence of IR was 39.6%. Subjects were divided into groups according to WC. A ‘normal’ WC was defined as below 88 cm in women and below 102 cm in men; ‘AO’ was defined as a WC equal to or above 88 cm in women and equal to or above 102 cm in men. The prevalence of IR was 31.7% in the group with normal WC and 54.6% in the AO group ( P
ISSN:0953-6205
1879-0828
DOI:10.1016/S0953-6205(03)00022-0