Alcohol consumption appears to protect against non‐alcoholic fatty liver disease

Aliment Pharmacol Ther 2011; 33: 378–388 Summary Background  Moderate alcohol consumption may have certain beneficial effects against non‐alcoholic fatty liver disease, which is associated with metabolic syndrome. Aim  To determine the association between drinking pattern and fatty liver in Japanese...

Full description

Saved in:
Bibliographic Details
Published in:Alimentary pharmacology & therapeutics 2011-02, Vol.33 (3), p.378-388
Main Authors: Moriya, A., Iwasaki, Y., Ohguchi, S., Kayashima, E., Mitsumune, T., Taniguchi, H., Ikeda, F., Shiratori, Y., Yamamoto, K.
Format: Article
Language:English
Subjects:
Adult
Alcohol Drinking - adverse effects
Alcohol Drinking - epidemiology
Asian Continental Ancestry Group
Biological and medical sciences
Cross-Sectional Studies
Digestive system
Fatty Liver - epidemiology
Fatty Liver - etiology
Fatty Liver - prevention & control
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Japan - epidemiology
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Metabolic Syndrome - complications
Metabolic Syndrome - epidemiology
Middle Aged
Non-alcoholic Fatty Liver Disease
Other diseases. Semiology
Pharmacology. Drug treatments
Risk Factors
Statistics as Topic
Time Factors
Ultrasonography
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aliment Pharmacol Ther 2011; 33: 378–388 Summary Background  Moderate alcohol consumption may have certain beneficial effects against non‐alcoholic fatty liver disease, which is associated with metabolic syndrome. Aim  To determine the association between drinking pattern and fatty liver in Japanese men and women. Methods  A cross‐sectional study was performed with health checkup data including information concerning alcohol consumption and ultrasonographic assessment of fatty liver. Results  We analysed 4957 men and 2155 women without reported liver diseases (median age, 49 years). In men, 40% of nondrinkers and 28% of drinkers had fatty liver. Alcohol consumption was inversely associated with fatty liver (adjusted odds ratio, 0.54; 95% confidence interval, 0.46–0.63). The prevalence of fatty liver in each category of drinking frequency was 38% (1–3 days/week), 29% (4–6 days/week), and 24% (daily drinking); there was a significant inverse correlation between drinking frequency and the prevalence of fatty liver (P 
ISSN:0269-2813
1365-2036
DOI:10.1111/j.1365-2036.2010.04520.x