Cardiac Responses to Sympathetic Stimulation

The cardiac responses to stimulation of sympathetic nerves to the heart were studied both in thoracotomized and in intact unanesthetized dogs. The changes in heart rate, left ventricular pressure, right and left ventricular dimensions and systemic arterial pressures were recorded. The powerful effec...

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Bibliographic Details
Published in:Circulation research 1956-05, Vol.4 (3), p.302-307
Main Authors: Anzola, Jorge, Rushmer, Robert F
Format: Article
Language:English
Subjects:
Heart - physiology
Humans
Old Medline
Sympathetic Nervous System - physiology
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Summary:The cardiac responses to stimulation of sympathetic nerves to the heart were studied both in thoracotomized and in intact unanesthetized dogs. The changes in heart rate, left ventricular pressure, right and left ventricular dimensions and systemic arterial pressures were recorded. The powerful effects of sympathetic stimulation resemble cardiac responses to exercise more than those following administration of catecholamines. It is inferred that neural mechanisms may be more important for cardiac control during spontaneous activities than the circulating hormones.
ISSN:0009-7330
1524-4571
DOI:10.1161/01.RES.4.3.302