The Role of Postexercise Measurements in the Diagnosis of Peripheral Arterial Disease in HIV-Infected Patients

Peripheral arterial disease (PAD) is a marker of atherosclerosis, which is not well studied in the population with human immunodeficiency virus (HIV). We prospectively enrolled HIV-infected patients who had normal resting ankle-brachial index (rABI) readings. All participants performed either a trea...

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Bibliographic Details
Published in:Angiology 2011-01, Vol.62 (1), p.10-14
Main Authors: Qaqa, Ashraf Y., DeBari, Vincent A., Isbitan, A., Mohammad, N., Sison, R., Slim, Jihad, Perez, George, Shamoon, Fayez E.
Format: Article
Language:English
Subjects:
Age
Ankle
Arteriosclerosis
Biological and medical sciences
Blood and lymphatic vessels
Cardiology. Vascular system
Cardiovascular diseases
Diseases of the lymphatic vessels
Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous
Exercise
Female
HIV Infections - complications
Human immunodeficiency virus
Humans
Infection
Language
Male
Medical sciences
Middle Aged
Peripheral Arterial Disease - diagnosis
Peripheral Arterial Disease - epidemiology
Peripheral Arterial Disease - etiology
plantar flexion
Population studies
Pressure
Prevalence
Prospective Studies
Risk factors
Walking
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Summary:Peripheral arterial disease (PAD) is a marker of atherosclerosis, which is not well studied in the population with human immunodeficiency virus (HIV). We prospectively enrolled HIV-infected patients who had normal resting ankle-brachial index (rABI) readings. All participants performed either a treadmill walking test (TT) or pedal plantar flexion test (PFT). Patients were divided into 2 groups according to postexercise changes; PAD and No-PAD group. The 2 groups were compared with regard to established cardiovascular disease risk factors and other HIV infection parameters. Peripheral arterial disease was present in 30 (26.5%) of 113 consecutive HIV-infected patients included in the study. Mean age was 47 ± 10 years. The risk factors studied did not differ significantly among the 2 groups except for male gender, which was significantly associated with PAD (RR: 4.15; CI: 1.6 to 11.1: P < .0008). The prevalence of PAD, diagnosed by significant drop in postexercise ABI and ankle pressure in patients with HIV is high.
ISSN:0003-3197
1940-1574
DOI:10.1177/0003319710385339