Enzyme markers in inbred rat strains: genetics of new markers and strain profiles

Twenty-six inbred strains of the laboratory rat (Rattus norvegicus) were examined for electrophoretic variation at an estimated 97 genetic loci. In addition to previously documented markers, variation was observed for the enzymes aconitase, aldehyde dehydrogenase, and alkaline phosphatase. The genet...

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Bibliographic Details
Published in:Biochemical genetics 1984-08, Vol.22 (7-8), p.611-629
Main Authors: ADAMS, M, BAVERSTOCK, P. R, WATTS, C. H. S, GUTMAN, G. A
Format: Article
Language:English
Subjects:
Aconitate Hydratase - genetics
Aldehyde Dehydrogenase - genetics
Alkaline Phosphatase - genetics
Alleles
Animals
Biological and medical sciences
Classical genetics, quantitative genetics, hybrids
Enzymes - genetics
Female
Fundamental and applied biological sciences. Psychology
Genetic Linkage
Genetic Variation
Genetics of eukaryotes. Biological and molecular evolution
Male
Polymorphism, Genetic
Rats
Rats, Inbred Strains - genetics
Species Specificity
Vertebrata
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Summary:Twenty-six inbred strains of the laboratory rat (Rattus norvegicus) were examined for electrophoretic variation at an estimated 97 genetic loci. In addition to previously documented markers, variation was observed for the enzymes aconitase, aldehyde dehydrogenase, and alkaline phosphatase. The genetic basis of these markers (Acon-1, Ahd-2, and Akp-1) was confirmed. Linkage analysis between 35 pairwise comparisons revealed that the markers Fh-1 and Pep-3 are linked. The strain profiles of the 25 inbred strains at 11 electrophoretic markers are given.
ISSN:0006-2928
1573-4927
DOI:10.1007/BF00485848