Primary Ewing's sarcoma involving the bones of the head and neck

Ewing's sarcoma is a rare tumor of the bone. In the Intergroup Ewing's Sarcoma Study (IESS) approximately 4% of the primary bone tumors arose in the bones of the head and neck. The mean age of patients was 10.9 years; boys slightly dominated the group. Signs and symptoms were local in dist...

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Bibliographic Details
Published in:Cancer 1987-12, Vol.60 (11), p.2829-2840
Main Authors: Siegal, Gene P., Oliver, William R., Reinus, William R., Gilula, Louis A., Foulkes, Mary A., Kissane, John M., Askin, Frederic B.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Biological and medical sciences
Bone Neoplasms - diagnostic imaging
Bone Neoplasms - pathology
Bone Neoplasms - therapy
Child
Child, Preschool
Female
Head and Neck Neoplasms - diagnostic imaging
Head and Neck Neoplasms - pathology
Head and Neck Neoplasms - therapy
Histocytochemistry
Humans
Male
Medical sciences
Otorhinolaryngology (head neck, general aspects and miscellaneous)
Otorhinolaryngology. Stomatology
Phosphopyruvate Hydratase - analysis
Prognosis
Radiography
Sarcoma, Ewing - diagnostic imaging
Sarcoma, Ewing - pathology
Sarcoma, Ewing - therapy
Tumors
Citations: Items that this one cites
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Description
Summary:Ewing's sarcoma is a rare tumor of the bone. In the Intergroup Ewing's Sarcoma Study (IESS) approximately 4% of the primary bone tumors arose in the bones of the head and neck. The mean age of patients was 10.9 years; boys slightly dominated the group. Signs and symptoms were local in distribution, with a mass or swelling most frequent. As in other sites, we categorized the dominant histologic pattern as diffuse or filigree, the latter carrying a more unfavorable prognosis. The radiographic appearance may be atypical as compared to Ewing's sarcoma at other sites. Prognosis of head and neck Ewing's is significantly better than Ewing's sarcoma overall. The gnathic bones were commonly affected, yet there was no associated mortality. No patient with primary disease in the bones of the head and neck who survived for 5 years on any of the IESS protocols has subsequently died.
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(19871201)60:11<2829::AID-CNCR2820601139>3.0.CO;2-S