Oestrous Synchronization, Ovarian Superovulation and Intraspecific Transfers From a Closed Breeding Colony of Inbred SLA Miniature Pigs

The inbred SLA miniature pig is a unique animal model developed for organ transplantation studies and pre‐clinical experimental purposes. Reported oestrous synchronization and superovulation treatments were examined in two SLA haplotypes (AA and DD) to allow collection of embryos for both practical...

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Bibliographic Details
Published in:Reproduction in domestic animals 2010-12, Vol.45 (6), p.951-958
Main Authors: Arlaud, JJ, Baker, L, Williams, RL, French, AJ
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Embryo Transfer - veterinary
Embryos
Estrus Synchronization - methods
Female
Fundamental and applied biological sciences. Psychology
Haplotypes
Histocompatibility Antigens Class II - genetics
Hogs
Inbreeding
Mammalian reproduction. General aspects
Sexual Maturation
Superovulation - physiology
Swine
Swine, Miniature - genetics
Swine, Miniature - physiology
Vertebrates: reproduction
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Summary:The inbred SLA miniature pig is a unique animal model developed for organ transplantation studies and pre‐clinical experimental purposes. Reported oestrous synchronization and superovulation treatments were examined in two SLA haplotypes (AA and DD) to allow collection of embryos for both practical embryo transfer and experimental technologies from a closed breeding colony. Pre‐puberal miniature pigs were poor responders to oestrous synchronization treatments, while post‐puberal sows were equivalent to commercial sows. Following superovulation, the ovulation number (corpora .hemorrhagica) was higher (p  0.05). No difference in ovulation number between haplotypes was observed, which differs from the previous report (DD>AA). Collection of zygotes for pronuclear injection was the highest in the non‐cycling post‐puberal miniature pig group (p 
ISSN:0936-6768
1439-0531
DOI:10.1111/j.1439-0531.2009.01467.x