Are there antiendometrial antibodies in sera of women with endometriosis?

To identify and characterize the antiendometrial tissue specific antibody response in endometriosis patients. Retrospective. Industrial research laboratory. Twenty untreated women with laparoscopically diagnosed endometriosis, 10 healthy women without symptoms of endometriosis, 12 women in whom lapa...

Full description

Saved in:
Bibliographic Details
Published in:Fertility and sterility 1991-08, Vol.56 (2), p.235-241
Main Authors: Switchenko, Arthur C., Kauffman, Robert S., Becker, Martin
Format: Article
Language:English
Subjects:
Autoantibodies - blood
Biological and medical sciences
Blotting, Western
Endometriosis - immunology
Endometrium - immunology
Enzyme-Linked Immunosorbent Assay
Female
Female genital diseases
Fluorescent Antibody Technique
Gynecology. Andrology. Obstetrics
Hemagglutination Tests
Humans
Medical sciences
Non tumoral diseases
Retrospective Studies
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:To identify and characterize the antiendometrial tissue specific antibody response in endometriosis patients. Retrospective. Industrial research laboratory. Twenty untreated women with laparoscopically diagnosed endometriosis, 10 healthy women without symptoms of endometriosis, 12 women in whom laparoscopy failed to yield evidence of endometriosis, 10 healthy men, and 4 individuals with elevated titers of serum antinuclear antibodies. Several immunological methods have been employed including immunofluorescence, hemagglutination, enzyme-linked immunoabsorbent assays, and protein blotting. Contrary to reports in the literature, results of these analyses have failed to demonstrate the presence of detectable levels of antiendometrial immunoreactivity in sera from patients with endometriosis. The association of endometrial autoimmunity with endometriosis remains to be established.
ISSN:0015-0282
1556-5653
DOI:10.1016/S0015-0282(16)54478-1