A New Variant Chromosomal Translocation t(2;2)(p23;q23) in CD30+/Ki-1+ Anaplastic Large Cell Lymphoma

A case with a complex chromosome abnormality with a t(2;2)(p23;q23) in CD30+/Ki-1+ anaplastic large cell lymphoma (ALCL) is described. This chromosome aberration has not been reported previously in neoplastic diseases and was associated with T-cell phenotype and involvement of the nasopharynx by the...

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Bibliographic Details
Published in:Leukemia & lymphoma 1998-01, Vol.28 (5-6), p.613-616
Main Authors: Mitev, Lubomir, Christova, Svetlana, Hadjiev, Evgeni, Guenova, Margarita, Oucheva, Radka, Valkov, Ivan, Manolova, Yanka
Format: Article
Language:English
Subjects:
Aged
Chromosome abnormality
Chromosomes, Human, Pair 2
Humans
immunophenotyping
Karyotyping
Lymphoma, Large-Cell, Anaplastic - genetics
Male
non-Hodgkin's lymphoma
Translocation, Genetic
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Summary:A case with a complex chromosome abnormality with a t(2;2)(p23;q23) in CD30+/Ki-1+ anaplastic large cell lymphoma (ALCL) is described. This chromosome aberration has not been reported previously in neoplastic diseases and was associated with T-cell phenotype and involvement of the nasopharynx by the tumour.
ISSN:1042-8194
1029-2403
DOI:10.3109/10428199809058372