Quantitative Cerebral Perfusion SPECT in Systemic Lupus Erythematosus with Severe Central Nervous Involvement—Before and After Methylprednisolone Pulse Therapy

Severe cerebral involvement may occur in patients with systemic lupus erythematosus. Methylprednisolone pulse therapy is a management choice for those with severe cerebral involvement. However, its effectiveness is uncertain. This article describes Tc‐99m HMPAO cerebral perfusion singlephoton emissi...

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Bibliographic Details
Published in:Journal of neuroimaging 1998-01, Vol.8 (1), p.55-57
Main Authors: You, Dong-Ling, Tzen, Kai-Yuan, Kao, Pan-Fu, Tsai, Ming-Fong
Format: Article
Language:English
Subjects:
Adolescent
Central Nervous System Diseases - complications
Central Nervous System Diseases - diagnostic imaging
Cerebrovascular Circulation - drug effects
Female
Glucocorticoids - administration & dosage
Humans
Lupus Erythematosus, Systemic - complications
Lupus Erythematosus, Systemic - drug therapy
Methylprednisolone - administration & dosage
Tomography, Emission-Computed, Single-Photon
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Summary:Severe cerebral involvement may occur in patients with systemic lupus erythematosus. Methylprednisolone pulse therapy is a management choice for those with severe cerebral involvement. However, its effectiveness is uncertain. This article describes Tc‐99m HMPAO cerebral perfusion singlephoton emission computerized tomography to document the restoration of cerebral perfusion after methylprednisolone pulse therapy in a case of systemic lupus erythromatosus with severe cerebral manifestations.
ISSN:1051-2284
1552-6569
DOI:10.1111/jon19988155