Spiking Mortality of Turkey Poults: 2. Effect of Six Different in vitro Disinfection Techniques on Organ Homogenates Capable of Reproducing SMT

Spiking mortality of turkeys (SMT) is an infectious disease of 5-to-25-day-old turkey poults characterized by acute enteritis and bursal and thymic atrophy. It is reproducible by exposure to organ homogenates or contaminated litter. We studied methods potentially useful for decontamination of turkey...

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Bibliographic Details
Published in:Avian diseases 1997-10, Vol.41 (4), p.906-909
Main Authors: Brown, Tom P., Garcia, AnaPatricia, Kelly, Laura
Format: Article
Language:English
Subjects:
Animals
Atrophy - pathology
Atrophy - physiopathology
Atrophy - veterinary
Body weight
Body Weight - physiology
Bursa of Fabricius - pathology
Chemical solutions
Coronavirus
Coronavirus, Turkey - isolation & purification
Disinfection - methods
Enteritis
Enteritis, Transmissible, of Turkeys - pathology
Enteritis, Transmissible, of Turkeys - physiopathology
Female
Formaldehyde - pharmacology
Freeze drying
Housing, Animal
Hydrogen-Ion Concentration
In Vitro Techniques
Inoculum
Intestines - pathology
Intestines - virology
Mortality
Poultry Diseases - mortality
Poultry Diseases - pathology
Poultry Diseases - physiopathology
Poults
Sodium Chloride - pharmacology
Syndrome
Temperature
Thymus Gland - pathology
Time Factors
Turkeys
Virus Shedding
Viruses
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Summary:Spiking mortality of turkeys (SMT) is an infectious disease of 5-to-25-day-old turkey poults characterized by acute enteritis and bursal and thymic atrophy. It is reproducible by exposure to organ homogenates or contaminated litter. We studied methods potentially useful for decontamination of turkey houses contaminated with SMT. Organ homogenates capable of producing SMT and containing turkey intestinal coronavirus were exposed in vitro for 5 hr to either 5.0% NaCl, pH 2.0, pH 12, 1.0% formaldehyde, 57 C, or lyophilization. Results were assessed by oral gavage of treated inocula into 1-day-old turkeys and measurement of subsequent coronavirus shedding, growth rate, feed conversion, and mortality from 1 to 21 days of age. Formaldehyde treatment rendered the inoculum nonpathogenic, whereas other treatments failed to ameliorate its negative effects. /// El incremento súbito de la mortalidad en pavos es una enfermedad infecciosa en pavitos de 5 a 25 días de edad caracterizada por una enteritis aguda y atrofia de la bolsa y del timo. Esta enfermedad se puede reproducir por exposición de las aves a los homogenados de órganos o cama contaminada. Se estudiaron métodos de utilidad potencial para la descontaminación de galpones infectados con el agente productor del incremento súbito de la mortalidad. Homogenados capaces de inducir la enfermedad, que contenían coronavirus intestinales de pavos, se expusieron in vitro durante 5 horas a cada uno de los siguientes tratamientos: 5.0% de NaCl, pH 2.0, pH 12, formaldehído al 1%, temperatura de 57 C, ó a la liofilización. Los resultados se determinaron mediante la administración oral del inóculo tratado a pavitos de un día de edad y la posterior determinación de la eliminación de coronavirus, rata de crecimiento, conversión alimenticia y mortalidad de 1 a 21 días de edad. El tratamiento con formaldehído produjo un inóculo no patógeno, mientras que los otros tratamientos no disminuyeron los efectos negativos.
ISSN:0005-2086
1938-4351
DOI:10.2307/1592345