EFFECTS OF HALOTHANE ON MOTOR EVOKED POTENTIAL RECORDED IN THE EXTRADURAL SPACE

We studied the effects of supplementing nitrous oxide—oxygen anaesthesia with halothane (1 MAC end-tidal concentration) on the motor evoked potential recorded in the extradural space of eight patients before corrective surgery for idiopathic adolescent scoliosis. The motor cortex was stimulated elec...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1989-11, Vol.63 (5), p.561-564
Main Authors: LOUGHNAN, B.A., ANDERSON, S.K., HETREED, M.A., WESTON, P.F., BOYD, S.G., HALL, G.M.
Format: Article
Language:English
Subjects:
Adolescent
Anesthesia, Inhalation
Anesthesia, Intravenous
Biological and medical sciences
Drug toxicity and drugs side effects treatment
Epidural Space
Evoked Potentials - drug effects
Halothane - pharmacology
Humans
Medical sciences
Motor Cortex - drug effects
Pharmacology. Drug treatments
Propofol - pharmacology
Scoliosis - surgery
Time Factors
Toxicity: nervous system and muscle
Citations: Items that cite this one
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Summary:We studied the effects of supplementing nitrous oxide—oxygen anaesthesia with halothane (1 MAC end-tidal concentration) on the motor evoked potential recorded in the extradural space of eight patients before corrective surgery for idiopathic adolescent scoliosis. The motor cortex was stimulated electrically through the scalp. An additional eight patients in whom anaesthesia was supplemented with an infusion of propofol acted as a control group. Halothane had no significant effect on the amplitude or latency of the motor evoked potential. We conclude that halothane is unlikely to alter the interpretation of motor evoked potentials recorded extradurally during scoliosis surgery.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/63.5.561