Effect of HLA compatibility on liver transplantation: Is it a predictive factor of postoperative outcome?

In LIVER transplantation (LT), the role of HLA compatibility remains controversial. Indeed, several groups 1 report a beneficial effect of HLA matching on survival rates and the incidence of rejection, whereas others fail to demonstrate any advantage between poorly- and well-matched patients. 2,3 Th...

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Bibliographic Details
Published in:Transplantation proceedings 1997-08, Vol.29 (5), p.2332-2334
Main Authors: Meyer, C., Parissiadis, A., Compagnon, P., Nisand, G., Woehl-Jaegle, M.L., Ellero, B., Herrera, J., Boudjema, K., Tongio, M.M., Jaeck, D., Cinqualbre, J., Wolf, P.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Graft Survival
Histocompatibility Testing
HLA Antigens - immunology
Humans
Liver Transplantation - immunology
Liver, biliary tract, pancreas, portal circulation, spleen
Medical sciences
Predictive Value of Tests
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the digestive system
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Summary:In LIVER transplantation (LT), the role of HLA compatibility remains controversial. Indeed, several groups 1 report a beneficial effect of HLA matching on survival rates and the incidence of rejection, whereas others fail to demonstrate any advantage between poorly- and well-matched patients. 2,3 This retrospective study analyzes the effects of mismatches and crossmatches on liver-transplanted patients and graft survival as well as post-operative events.
ISSN:0041-1345
1873-2623
DOI:10.1016/S0041-1345(97)00389-8