Nucleotide sequence and phylogenetic analysis of Newcastle disease virus isolates from recent outbreaks in Taiwan

Portion: of the hemagglutinin neuraminidase (HN) gene of Newcastle disease virus (NDV) isolates from two recent outbreaks were sequenced to investigate epidemiology of this disease in Taiwan. These NDV isolates were all viscerotropic velogenic according to the clinical lesions produced in chickens....

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Bibliographic Details
Published in:Avian diseases 1997-04, Vol.41 (2), p.365-373
Main Authors: Yang, C.Y. (National Chung Hsing University, Taichung, Taiwan.), Chang, P.C, Hwang, J.M, Shieh, H.K
Format: Article
Language:English
Subjects:
Amino Acid Sequence
Animals
Atrophy
Base Sequence
Bone Marrow - pathology
Cell Line
Chickens
COMPOSICION QUIMICA
COMPOSITION CHIMIQUE
Consensus Sequence
Disease outbreaks
Disease Outbreaks - veterinary
Disease Susceptibility
DNA Primers
EPIDEMIOLOGIA
EPIDEMIOLOGIE
Epidemiology
FILOGENIA
GENE
GENES
Hemagglutinins, Viral - chemistry
Hemagglutinins, Viral - genetics
Hematocrit
Molecular Sequence Data
Nervous system diseases
Neuraminidase - chemistry
Neuraminidase - genetics
Newcastle disease
Newcastle Disease - epidemiology
Newcastle Disease - pathology
Newcastle Disease - virology
Newcastle disease virus
Newcastle disease virus - classification
Newcastle disease virus - genetics
Newcastle disease virus - isolation & purification
Nucleotide sequences
Nucleotides
Phylogenetics
PHYLOGENIE
Phylogeny
POLLO
Polymerase Chain Reaction
POULET
SECUENCIA NUCLEOTIDICA
SEQUENCE NUCLEOTIDIQUE
TAIWAN
Taiwan - epidemiology
Thymus Gland - pathology
VIRUS DE LA ENFERMEDAD DE NEWCASTLE
VIRUS MALADIE DE NEWCASTLE
Viruses
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Description
Summary:Portion: of the hemagglutinin neuraminidase (HN) gene of Newcastle disease virus (NDV) isolates from two recent outbreaks were sequenced to investigate epidemiology of this disease in Taiwan. These NDV isolates were all viscerotropic velogenic according to the clinical lesions produced in chickens. Sequence data were obtained from 14 NDV isolates (12 from 1995 arid 2 from 1984). All isolates differed in their nucleotide sequences (from 0.3 to 15.3%), and represented potentially different strains of NDV. Phylogenetic analysis revealed that these isolates are closely related to viruses isolated from Japan and Malaysia. Some viruses isolated in 1995 appeared to evolve from viruses isolated in 1984. The results suggest that the 1995 outbreak of Newcastle disease (ND) in Taiwan may have been caused by multiple strains of velogenic NDV that have cocirculated in Taiwan for some time. Moreover, NDV isolates from racing pigeons were very similar to isolates from chickens in the same period, suggesting that both domestic and free-living birds were involved in the spread of ND in Taiwan
ISSN:0005-2086
1938-4351
DOI:10.2307/1592191