The onychomatricoma: an electron microscopic study

The electron microscopic findings in the onychomatricoma are described. In the proximal zone of the onychomatricoma, basal cells have various aspects, some being lacunar while others have only a limited cytoplasmic rim containing mitochondria and tonofilaments. In the parakeratotic cell columns the...

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Bibliographic Details
Published in:Journal of cutaneous pathology 1997-03, Vol.24 (3), p.183-188
Main Authors: Kint, A., Baran, R., Geerts, M.L.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Dermatology
Female
Humans
Male
Medical sciences
Middle Aged
Nail Diseases - pathology
Nails - pathology
Nails - ultrastructure
Neoplasms - pathology
Neoplasms - ultrastructure
Stromal Cells - pathology
Stromal Cells - ultrastructure
Tumors of the skin and soft tissue. Premalignant lesions
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Summary:The electron microscopic findings in the onychomatricoma are described. In the proximal zone of the onychomatricoma, basal cells have various aspects, some being lacunar while others have only a limited cytoplasmic rim containing mitochondria and tonofilaments. In the parakeratotic cell columns the cells elongate and homogenized tonofilaments appear. Around the lacunae the cells are poorly differentiated and their cytoplasm is granular. It can be concluded that in an onychomatricoma the basal cells have a decreased amount of tonofilaments and desmosomes and that their evolution is not uniform. The tumour can be considered as being the result of a disturbed differentiation of nail matrix cells.
ISSN:0303-6987
1600-0560
DOI:10.1111/j.1600-0560.1997.tb01574.x