Diterpenoids from the Roots of Salvia hypargeia

From the root extracts of Salvia hypargeia, in addition to the known diterpenoids cryptanol and horminone, six new abietane diterpenoids were isolated. The structures of the new and the known compounds were established by spectral data. The new compounds, hypargenins A, B, C, D, and F, showed antiba...

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Bibliographic Details
Published in:Journal of natural products (Washington, D.C.) D.C.), 1988-11, Vol.51 (6), p.1178-1183
Main Authors: Ulubelen, Ayhan, Evren, Namik, Tuzlaci, Ertan, Johansson, Candan
Format: Article
Language:English
Subjects:
AISLAMIENTO (TECNICA)
Anti-Infective Agents - isolation & purification
ANTIMICROBIALS
ANTIMICROBIANO
ANTIMICROBIEN
Biological and medical sciences
Diterpenes - isolation & purification
Diterpenes - pharmacology
General pharmacology
HIDROCARBUROS
HYDROCARBONS
HYDROCARBURE
ISOLATION
ISOLEMENT
Magnetic Resonance Spectroscopy
Medical sciences
Microbial Sensitivity Tests
Molecular Structure
Pharmacognosy. Homeopathy. Health food
Pharmacology. Drug treatments
Plants - analysis
RACINE
RAICES
ROOTS
SALVIA
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Summary:From the root extracts of Salvia hypargeia, in addition to the known diterpenoids cryptanol and horminone, six new abietane diterpenoids were isolated. The structures of the new and the known compounds were established by spectral data. The new compounds, hypargenins A, B, C, D, and F, showed antibacterial activity, while hypargenin F was also active against Mycobacterium tuberculosis. Hypargenin E did not exhibit antibacterial activity.
ISSN:0163-3864
1520-6025
DOI:10.1021/np50060a021