Chlamydial Serology Among Patients with Tubal Factor Infertility and Ectopic Pregnancy in Alexandria, Egypt

Background and Objectives: Little is known about the role of Chlamydia trachomatis in the etiology of tubal factor infertility and ectopic pregnancy in Egypt Goal of this Study: To assess the association between past chlamydial infection, tubal factor infertility, and ectopic pregnancy in an Egyptia...

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Bibliographic Details
Published in:Sexually transmitted diseases 1995-09, Vol.22 (5), p.317-321
Main Authors: MEHANNA, MOHAMMED T. R., RIZK, MOHAMAD A., EWEISS, NAGWA YOUSSEF M., RAMADAN, MOHAMAD, ZAKI, SOAD A., SADEK, ALY, CHOW, JOAN M., SCHACHTER, JULIUS
Format: Article
Language:English
Subjects:
Adult
Antibodies, Bacterial - blood
Biological and medical sciences
Birth control
Case-Control Studies
Chlamydia Infections - complications
Chlamydia Infections - epidemiology
Chlamydia Infections - immunology
Chlamydia trachomatis - immunology
Egypt - epidemiology
Female
Fertility
Gynecology. Andrology. Obstetrics
Humans
Infertility, Female - epidemiology
Infertility, Female - immunology
Infertility, Female - microbiology
Medical sciences
Original Articles
Population
Pregnancy
Pregnancy, Ectopic - epidemiology
Pregnancy, Ectopic - immunology
Pregnancy, Ectopic - microbiology
Prevalence
Sexually transmitted diseases
STD
Sterility. Assisted procreation
Tropical medicine
Women
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Summary:Background and Objectives: Little is known about the role of Chlamydia trachomatis in the etiology of tubal factor infertility and ectopic pregnancy in Egypt Goal of this Study: To assess the association between past chlamydial infection, tubal factor infertility, and ectopic pregnancy in an Egyptian population. Study Design: This report consists of two concurrent case-control studies. First, 51 patients with tubal factor infertility were compared with 48 healthy subjects who did not have tubal factor infertility and 53 pregnant subject subjects. Second, 66 patients with ectopic pregnancy were compared with 51 pregnant control subjects. Results: Geometric mean titers for Chlamydia trachomatis were higher among patients with tubal factor infertility and ectopic pregnancy, and they were more likely to have high antichlamydial titers (≥1:128 immunoglobulin G). Serum titer was significantly correlated with histologie evidence of salpingitis among the patients with an ectopic pregnancy. Conclusion: Our findings, similar to those from Western societies, suggest that among Egyptian women, prior chlamydial infection is associated with an increased risk of tubal factor infertility and possibly ectopic pregnancy.
ISSN:0148-5717
1537-4521
DOI:10.1097/00007435-199509000-00009