Relationship of plasma level of vitamin C to mortality from ischemic heart disease

The present epidemiological data support and extend previous evidence in men and animals. Thus, a poor plasma status of vitamin C (less than 23 microM = 0.4 mg/dl) and/or of cholesterol-standardized vitamin E (less than 20-21.5 microM = 9 mg/l) occurs in westernized countries with an increased risk...

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Bibliographic Details
Published in:Annals of the New York Academy of Sciences 1987, Vol.498 (1), p.110-123
Main Authors: Gey, K.F, Stahelin, H.B, Puska, P, Evans, A
Format: Article
Language:English
Subjects:
ACIDE ASCORBIQUE
ACIDO ASCORBICO
Adult
ASCORBIC ACID
Ascorbic Acid - blood
CARDIOPATHIE
CARENCE EN VITAMINES
CHOLESTEROL
Cholesterol - blood
COLESTEROL
Coronary Disease - blood
Coronary Disease - epidemiology
Coronary Disease - mortality
Cross-Sectional Studies
DEFICIENCIA DE VITAMINAS
ENFERMEDADES CARDIACAS
Finland
HEART DISEASES
Humans
Ireland
Italy
Male
Middle Aged
MORTALIDAD
MORTALITE
MORTALITY
Prospective Studies
Risk
Scotland
Switzerland
VITAMIN DEFICIENCIES
Vitamin E - blood
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Summary:The present epidemiological data support and extend previous evidence in men and animals. Thus, a poor plasma status of vitamin C (less than 23 microM = 0.4 mg/dl) and/or of cholesterol-standardized vitamin E (less than 20-21.5 microM = 9 mg/l) occurs in westernized countries with an increased risk of IHD. A poor status in the major essential antioxidants may be a hitherto underrated, at least permissive, risk factor of IHD that could, at least in some European countries, substantially complement the previously established risk factors such as hypercholesterolemia.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1987.tb23755.x