Comparative studies on activities of antimicrobial agents against causative organisms isolated from urinary tract infections (1989). III. Secular changes in susceptibility

Susceptibilities of Citrobacter spp., Enterobacter spp., Escherichia coli, Klebsiella spp., Proteus mirabilis, Pseudomonas aeruginosa, Serratia spp. isolated from patients with urinary tract infections (UTIs) in 10 hospitals during June 1989 to May 1990 to various antimicrobial agents were compared...

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Bibliographic Details
Published in:Japanese journal of antibiotics 1995-09, Vol.48 (9), p.1174-1263
Main Authors: Kumamoto, Y, Hirose, T, Tanaka, N, Hikichi, Y, Shigeta, S, Shiraiwa, Y, Kameoka, H, Yoshida, H, Ogata, M, Tazaki, H
Format: Article
Language:Japanese
Subjects:
Anti-Bacterial Agents - pharmacology
Anti-Infective Agents, Urinary - pharmacology
Bacteria - drug effects
Bacteria - isolation & purification
Bacterial Infections - microbiology
Citrobacter - drug effects
Enterobacter - drug effects
Escherichia coli - drug effects
Humans
Klebsiella - drug effects
Microbial Sensitivity Tests
Proteus mirabilis - drug effects
Pseudomonas aeruginosa - drug effects
Serratia - drug effects
Urinary Catheterization
Urinary Tract Infections - microbiology
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Summary:Susceptibilities of Citrobacter spp., Enterobacter spp., Escherichia coli, Klebsiella spp., Proteus mirabilis, Pseudomonas aeruginosa, Serratia spp. isolated from patients with urinary tract infections (UTIs) in 10 hospitals during June 1989 to May 1990 to various antimicrobial agents were compared with those in the same period of previous years according to a classification, uncomplicated UTIs, complicated UTIs without indwelling catheter, and complicated UTIs with indwelling catheter. As for Citrobacter spp., P. mirabilis and Serratia spp., which were detected very few in 1989, their susceptibilities were not observed an obvious change. As for Enterobacter spp., the susceptible strains to flomoxef, cefixime, cefuzonam and ceftazidime increased in complicated UTIs with indwelling catheter. The susceptibilities of E. coli to penicillins increased slightly in complicated UTIs with indwelling catheter. Against Klebsiella spp., a good activity of minocycline or cephems was found. The susceptibilities of P. aeruginosa to ciprofloxacin and new quinolones increased in uncomplicated UTIs. These data should be considered in clinical treatment of various urinary tract infections.
ISSN:0368-2781
DOI:10.11553/antibiotics1968b.48.1174