Extradural ropivacaine and bupivacaine in hip surgery

We studied 126 patients undergoing elective hip surgery; they received 20 ml of 0.5%, 0.75%, 1.0% ropivacaine or 0.5% bupivacaine extradurally in a double-blind design. Sensory block (pinprick), motor block (modified Bromage scale), quality of analgesia and neuromuscular block were assessed intermit...

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Bibliographic Details
Published in:British Journal of Anaesthesia 1995-04, Vol.74 (4), p.458-460
Main Authors: WOLFF, A.P., HASSELSTRÖM, L., KERKKAMP, H.E., GIELEN, M.J.
Format: Article
Language:English
Subjects:
Aged
Amides
Anaesthetic techniques
Anaesthetic techniques, extradural
Anaesthetics local
Anaesthetics local, bupivacaine
Anaesthetics local, ropivacaine
Analgesia, Epidural
Anesthesia, Spinal
Anesthetics. Neuromuscular blocking agents
Biological and medical sciences
Blood Pressure
Bupivacaine
Double-Blind Method
Elective Surgical Procedures
extradural
Female
Heart Rate
Hip Prosthesis
Humans
Male
Medical sciences
Middle Aged
Nerve Block
Neuropharmacology
orthopaedic
Pharmacology. Drug treatments
Prospective Studies
Ropivacaine
Surgery
Surgery, orthopaedic
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Summary:We studied 126 patients undergoing elective hip surgery; they received 20 ml of 0.5%, 0.75%, 1.0% ropivacaine or 0.5% bupivacaine extradurally in a double-blind design. Sensory block (pinprick), motor block (modified Bromage scale), quality of analgesia and neuromuscular block were assessed intermittently. Heart rate and arterial pressure were measured at regular intervals. A total of 115 patients were evaluated for efficacy. Onset of analgesia, onset of motor block and maximum cephalad spread (T4) did not differ between the groups. Duration and quality of analgesia and motor block increased with the concentration of ropivacaine. Ropivacaine 1.0% provided a longer duration of analgesia and motor block, more intense motor block and more patients with satisfactory analgesia than 0.5% bupivacaine. More patients treated with the higher concentrations of ropivacaine required treatment for hypotension and bradycardia.
ISSN:0007-0912
1471-6771
1471-6771
DOI:10.1093/bja/74.4.458