Levels of CA-19.9, CA-125, and CA-195 in seminal plasma and in vitro fertilization rates

To assess the relationship between carbohydrate tumor markers in seminal plasma and fertilization rates in IVF cycles. Prospective study. Academic tertiary hospital. Forty-six consecutive couples subjected to IVF in which at least one oocyte was obtained. Determination of CA-19.9, CA-125, and CA-195...

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Bibliographic Details
Published in:Fertility and sterility 1995-03, Vol.63 (3), p.604-607
Main Authors: Matorras, Roberto, Genollá, José, Diez, Javier, Corcóstegui, Beatriz, Neyro, Jose Luis, Fombellida, Juan Cruz, Rodríguez-Escudero, Francisco Javier
Format: Article
Language:English
Subjects:
Antigens, Tumor-Associated, Carbohydrate - analysis
Biological and medical sciences
Biomarkers - analysis
Birth control
CA-125
CA-125 Antigen - analysis
CA-19-9 Antigen - analysis
CA-19.9
CA-195
Female
Fertilization in Vitro
Gynecology. Andrology. Obstetrics
Humans
in vitro fertilization
Male
Medical sciences
Pregnancy
prognosis
Prospective Studies
Reference Values
Semen - chemistry
seminal plasma
Sterility. Assisted procreation
Tumor marker
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Summary:To assess the relationship between carbohydrate tumor markers in seminal plasma and fertilization rates in IVF cycles. Prospective study. Academic tertiary hospital. Forty-six consecutive couples subjected to IVF in which at least one oocyte was obtained. Determination of CA-19.9, CA-125, and CA-195 in seminal plasma 1 week before IVF. CA-125 was higher in the group without fertilization (321±198 U/mL, mean±SD) than in the group in which at least one oocyte was fertilized (155±165 U/mL), whereas CA-19.9 and CA-195 were similar in both groups. However, at the cutoff 66%, lower values of CA-19.9 were found in the fertilization group rate
ISSN:0015-0282
1556-5653
DOI:10.1016/S0015-0282(16)57433-0