Peritoneal dialysis in an infant with Type 1 diabetes and hyperosmolar coma

Hyperosmolar coma which is characterized by severe hyperglycemia in absence of chetosis is very rare in pediatric age with only 11 cases reported in the literature. The outcome of the condition is usually poor with mental retardation being the most common event. Here a case of hyperosmolar coma is d...

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Bibliographic Details
Published in:Journal of endocrinological investigation 2001-02, Vol.24 (2), p.104-106
Main Authors: MULTARI, G, WERNER, B, CERVONI, M, LUBRANO, R, COSTANTINO, F, DEMIRAJ, V, POZZILLI, P
Format: Article
Language:English
Subjects:
Acidosis, Lactic - complications
Associated diseases and complications
Biological and medical sciences
Dehydration - complications
Diabetes Mellitus, Type 1 - complications
Diabetes Mellitus, Type 1 - therapy
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Female
Follow-Up Studies
Humans
Hyperglycemia - complications
Hyperglycemic Hyperosmolar Nonketotic Coma - etiology
Hyperglycemic Hyperosmolar Nonketotic Coma - therapy
Hypernatremia - complications
Infant
Insulin - therapeutic use
Lactic Acid - blood
Medical sciences
Peritoneal Dialysis
Seizures - complications
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Summary:Hyperosmolar coma which is characterized by severe hyperglycemia in absence of chetosis is very rare in pediatric age with only 11 cases reported in the literature. The outcome of the condition is usually poor with mental retardation being the most common event. Here a case of hyperosmolar coma is described in a female of three months of age who was treated with peritoneal dialysis 11 hours after admittance to hospital. This female patient has been receiving insulin from three months of age and today at the age of 10 years she leads a normal life despite being on insulin therapy. A very low level of C-peptide (
ISSN:0391-4097
1720-8386
DOI:10.1007/BF03343822