Prevention of measles in Sudan: a prospective study on vaccination, diagnosis and epidemiology

Despite the availability of safe and effective live attenuated vaccines, measles continues to be endemic in many developing countries. Control and elimination of measles will be especially difficult in East Africa, because of its limited infrastructure and political instability. We have studied diag...

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Bibliographic Details
Published in:Vaccine 2001-03, Vol.19 (17), p.2254-2257
Main Authors: de Swart, Rik L., El Mubarak, H.Sittana, Vos, Helma W., Mustafa, Omer M., Abdallah, Abdallah, Groen, Jan, Mukhtar, Maowia M., Zijlstra, Edward E., El Hassan, Ahmed M., Wild, T.Fabian, Ibrahim, Salah A., Osterhaus, Albert D.M.E.
Format: Article
Language:English
Subjects:
Antibodies, Viral - blood
Biological and medical sciences
Cohort Studies
Diagnosis
Epidemiology
Epidemiology. Vaccinations
General aspects
Humans
Infant
Infant, Newborn
Infectious diseases
Measles
Measles - diagnosis
Measles - epidemiology
Measles - prevention & control
Measles Vaccine - pharmacology
measles virus
Measles virus - genetics
Measles virus - immunology
Measles virus - isolation & purification
Medical sciences
Prospective Studies
Reverse Transcriptase Polymerase Chain Reaction
Seroepidemiologic Studies
Serologic Tests
Sudan
Sudan - epidemiology
Vaccination
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Summary:Despite the availability of safe and effective live attenuated vaccines, measles continues to be endemic in many developing countries. Control and elimination of measles will be especially difficult in East Africa, because of its limited infrastructure and political instability. We have studied diagnostic and epidemiological aspects of measles in suburban Khartoum, Sudan. Prospective studies were carried out in a cohort of clinically diagnosed measles cases and in a cohort of new-borns, which were both followed up for 2 years. The studies intended to provide a rational basis for improvement of measles vaccination strategies, and strengthen measles research infrastructure in Khartoum.
ISSN:0264-410X
1873-2518
DOI:10.1016/S0264-410X(00)00548-X