Development of Anticipatory Nausea: A Prospective Analysis

The development of anticipatory nausea in cancer chemotherapy typically has been viewed in terms of a respondent learning model. Firm support for this etiological model has been precluded by use of retrospective research designs, however. The present study employed a prospective design to identify p...

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Bibliographic Details
Published in:Journal of consulting and clinical psychology 1985-08, Vol.53 (4), p.447-454
Main Authors: Andrykowski, Michael A, Redd, William H, Hatfield, Alan K
Format: Article
Language:English
Subjects:
Antineoplastic Agents - adverse effects
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Biological and medical sciences
Chemotherapy
Client Characteristics
Drug Therapy
Female
Fundamental and applied biological sciences. Psychology
Human
Humans
Illness and personality
Male
Medical Patients
Middle Aged
Nausea
Nausea - chemically induced
Nausea - psychology
Neoplasms
Neoplasms - drug therapy
Psychology and medicine
Psychology. Psychoanalysis. Psychiatry
Psychology. Psychophysiology
Set (Psychology)
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Summary:The development of anticipatory nausea in cancer chemotherapy typically has been viewed in terms of a respondent learning model. Firm support for this etiological model has been precluded by use of retrospective research designs, however. The present study employed a prospective design to identify patient- and treatment-related variables characteristic of patients who subsequently develop anticipatory nausea. Seventy-one chemotherapy outpatients were interviewed before and after each chemotherapy infusion during their first 6 months of treatment. Hierarchical multiple regression analysis revealed that patients who developed anticipatory nausea were characterized by more severe posttreatment nausea, more time-consuming treatment infusions, and greater state anxiety relative to patients without anticipatory nausea. In general, results supported a respondent learning conceptualization of the development of anticipatory nausea. Clinical implications of these findings for the prevention of anticipatory nausea are suggested.
ISSN:0022-006X
1939-2117
DOI:10.1037/0022-006X.53.4.447