Early Complications after Nipple-Sparing Mastectomy and Immediate Breast Reconstruction with Silicone Prosthesis: Results of 214 Procedures

Background and Aims: Breast reconstruction with silicone prosthesis following nipple-sparing mastectomy has become widely accepted as a reconstruction option in women requiring mastectomy for cancer. The purpose of this study was to evaluate the incidence and some factors influencing early local com...

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Bibliographic Details
Published in:Scandinavian journal of surgery 2010-01, Vol.99 (3), p.115-118
Main Authors: Radovanovic, Z., Radovanovic, D., Golubovic, A., Ivkovic-Kapicl, T., Bokorov, B., Mandic, A.
Format: Article
Language:English
Subjects:
Adult
Aged
Breast Implantation
Breast Implants
Breast Neoplasms - drug therapy
Breast Neoplasms - radiotherapy
Breast Neoplasms - surgery
Chemotherapy, Adjuvant
Female
Humans
Mastectomy - adverse effects
Mastectomy - methods
Middle Aged
Necrosis
Postoperative Complications - epidemiology
Prospective Studies
Radiotherapy, Adjuvant
Seroma - epidemiology
Silicone Elastomers
Skin - pathology
Treatment Outcome
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Summary:Background and Aims: Breast reconstruction with silicone prosthesis following nipple-sparing mastectomy has become widely accepted as a reconstruction option in women requiring mastectomy for cancer. The purpose of this study was to evaluate the incidence and some factors influencing early local complications in patients undergoing NSM with immediate implant reconstruction. Material and Methods: Prospective study was performed on a consecutive series of 214 breast reconstructions in 205 patients. All complications during the six weeks after surgery were recorded. 42 prostheses were implanted after neoadjuvant chemotherapy, 27 patients previously had radiotherapy due to breast conserving surgery and in all other cases surgery was the primary treatment for cancer. Results: The overall six-week complication rate was 16% (35) and included: major skin flap necrosis (4%, 9 procedures), minor skin necrosis (3%, 7), major infection (2%, 5), minor infection (3%, 7), prolonged seroma formation (3%, 6), haematoma (1%, 2) and epidermolysis (1%, 2). In 6% (12) reconstruction procedures explantation of prosthesis was done. Neoadjuvant chemotherapy and radiotherapy were not associated with higher rate of complications. Conclusion: Nipple-sparing mastectomy with immediate implant reconstruction has acceptable morbidity rate in the hand of experienced oncoplastic surgeon and therefore should be considered as treatment option to women requiring mastectomy.
ISSN:1457-4969
1799-7267
DOI:10.1177/145749691009900302