Gold nanorods for platinum based prodrug delivery

PEGylated gold nanorods (PEG-GNRs) conjugate with Pt(iv) prodrug as a drug delivery system, showing superior cytotoxicity compared to cisplatin against different types of cancer cells.

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Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2010-11, Vol.46 (44), p.8424-8426
Main Authors: Min, Yuanzeng, Mao, Chengqiong, Xu, Dechen, Wang, Jun, Liu, Yangzhong
Format: Article
Language:English
Subjects:
Cell Line, Tumor
Cisplatin - toxicity
Drug Carriers - chemistry
Gold - chemistry
Humans
Nanotubes - chemistry
Nanotubes - toxicity
Platinum - chemistry
Polyethylene Glycols - chemistry
Prodrugs - administration & dosage
Prodrugs - toxicity
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Description
Summary:PEGylated gold nanorods (PEG-GNRs) conjugate with Pt(iv) prodrug as a drug delivery system, showing superior cytotoxicity compared to cisplatin against different types of cancer cells.
ISSN:1359-7345
1364-548X
DOI:10.1039/c0cc03108a