Characteristics and prognosis of chromophobe non-metastatic renal cell carcinoma: A multicenter study

Objectives:  To analyze the characteristics and the prognostic significance of chromophobe renal cell carcinomas (chRCC). Methods:  Data about 2981 patients with non‐metastatic renal cell carcinomas (RCC) at the time of surgery were retrospectively collected from 26 institutions between 1998 and 200...

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Bibliographic Details
Published in:International journal of urology 2010-11, Vol.17 (11), p.898-904
Main Authors: Lee, Won Ki, Byun, Seok-Soo, Kim, Hyeon Hoe, Rha, Koon Ho, Hwang, Tae-Kon, Sung, Gyung Tak, Lee, Wan, Lim, Jae Sung, Jeong, Young Beom, Kwon, Tae Gyun
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Aged
Analysis of Variance
Biopsy, Needle
Carcinoma, Renal Cell - mortality
Carcinoma, Renal Cell - pathology
Carcinoma, Renal Cell - secondary
Carcinoma, Renal Cell - therapy
chromophobe
Cohort Studies
Combined Modality Therapy
Confidence Intervals
conventional
Disease-Free Survival
Female
Humans
Immunohistochemistry
Kaplan-Meier Estimate
Kidney Neoplasms - mortality
Kidney Neoplasms - pathology
Kidney Neoplasms - therapy
Male
Middle Aged
Multivariate Analysis
Neoplasm Invasiveness - pathology
Neoplasm Staging
Nephrectomy - methods
pathology
Prognosis
Proportional Hazards Models
renal cell carcinoma
Retrospective Studies
Risk Assessment
Sex Factors
survival
Survival Analysis
Young Adult
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Summary:Objectives:  To analyze the characteristics and the prognostic significance of chromophobe renal cell carcinomas (chRCC). Methods:  Data about 2981 patients with non‐metastatic renal cell carcinomas (RCC) at the time of surgery were retrospectively collected from 26 institutions between 1998 and 2008. All patients had undergone partial or radical nephrectomies. Of the 2981 patients, 2602 patients with conventional RCC (cRCC) and 148 with chRCC were studied. Clinical and pathological parameters were determined in all patients. Recurrence‐free survival (RFS) and cancer‐specific survival (CSS) were assessed. Results:  Patients with chRCC differed significantly from those with cRCC on the following parameters: younger age (P = 0.026), greater female ratio (P 
ISSN:0919-8172
1442-2042
DOI:10.1111/j.1442-2042.2010.02630.x